Copper Nicotinate

Synonyms: Copper Nicotinate, Nicotinic acid copper salt, Copper(II) nicotinate, Copper pyridine-3-carboxylate, Bis(nicotinato)copper(II), Copper nicotinate complex

Copper Nicotinate is a coordination compound formed between copper(II) ions and nicotinic acid (vitamin B3) ligands, typically in a 1:2 metal-to-ligand ratio. This complex combines the essential trace element copper with the vitamin B3 derivative, offering a dual-action ingredient that has garnered interest in pharmaceutical, nutraceutical, and cosmetic applications. Unlike simple copper salts, the chelated structure of Copper Nicotinate enhances its stability and may improve bioavailability, making it a preferred choice for formulators seeking efficient delivery of both copper and niacin.

Chemically, Copper Nicotinate belongs to the family of metal carboxylate complexes. The nicotinate ligands coordinate to the copper center through the carboxylate oxygen and the pyridine nitrogen, creating a distorted octahedral geometry. This chelation imparts unique electronic properties, including a characteristic blue-green color and paramagnetic behavior. The compound is relatively stable under normal conditions but should be protected from moisture and strong oxidizing agents to prevent decomposition.

In the nutraceutical industry, Copper Nicotinate is used as a source of copper in dietary supplements, often in combination with other minerals. Copper is an essential cofactor for numerous enzymes, including superoxide dismutase and cytochrome c oxidase, and plays a critical role in iron metabolism, connective tissue formation, and antioxidant defense. The nicotinate component may also contribute to vasodilation and lipid metabolism support, although these effects are primarily associated with nicotinic acid at higher doses. In cosmetics, Copper Nicotinate is explored for its potential in skin care formulations targeting wound healing and anti-aging, leveraging copper’s role in collagen synthesis and its antimicrobial properties.

For research and industrial applications, Copper Nicotinate is available in high-purity grades, typically ≥98% as determined by HPLC. It is supplied as a fine crystalline powder, compatible with various formulation processes. Our production adheres to strict quality control measures, ensuring consistent particle size, low heavy metal content, and reliable batch-to-batch uniformity.

Function

• Enzyme cofactor: Copper is integral to the function of superoxide dismutase, cytochrome c oxidase, and tyrosinase, supporting antioxidant defense and energy metabolism.
• Iron metabolism: Copper facilitates the mobilization and utilization of iron, aiding in hemoglobin synthesis and preventing anemia.
• Connective tissue support: Copper-dependent lysyl oxidase is essential for collagen and elastin cross-linking, promoting skin and vascular integrity.
• Antimicrobial activity: Copper ions exhibit broad-spectrum antimicrobial effects, useful in topical formulations and coatings.
• Niacin supplementation: Provides a source of nicotinic acid, which supports NAD+ synthesis and cellular energy production.

Source & Standardization

• Source: Synthetic complexation of copper(II) salts with nicotinic acid.
• Extraction: Not applicable; produced via controlled chemical reaction and crystallization.
• Standardization: ≥98.0% assay (HPLC), with strict limits on heavy metals and residual solvents.
• Forms: Blue to blue-green crystalline powder.
• Applications: Dietary supplements, pharmaceutical intermediates, cosmetic actives, research reagents.

Specifications

Documentation & Supply

• Monthly capacity: 500 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 25 kg fiber drums with double polyethylene liners, customizable packaging for small quantities

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com