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Deoxyarbutin is a next-generation cosmetic active ingredient for skin brightening and lightening.
It is primarily used in advanced whitening and depigmenting cosmetic formulations.
As a highly potent tyrosinase inhibitor, Deoxyarbutin effectively regulates melanin production, helps overcome hyperpigmentation, and fades dark spots, delivering fast and long-lasting skin lightening effects. Additionally, Deoxyarbutin exhibits strong antioxidant properties.
Its inhibitory effect on tyrosinase is significantly superior to other common brightening agents.
Studies have shown Deoxyarbutin to be 350 times more effective than Arbutin, 150 times more effective than Kojic Acid, and 10 times more effective than Hydroquinone.
Compared to these traditional agents, Deoxyarbutin offers a higher safety profile and greater stability.
It is non-toxic, non-irritating to the skin, and is easily absorbed. Effective skin brightening results can be achieved even at low usage levels, making Deoxyarbutin a widely recognized, very safe cosmetic whitening active ingredient.

C11H14O3
Primary applications:
Cosmetic research & development
Skin depigmentation studies
Anti-melanogenesis assays
High-end topical formulation testing
Key synonyms:
4-[(Tetrahydro-2H-pyran-2-yl)oxy]phenol
Deoxyarbutin (INCI name)
| ITEM | Specification | Test Method |
|---|---|---|
| Assay (HPLC) | ≥ 99.0% | HPLC-UV |
| Appearance | White to off-white crystalline powder | Visual |
| Identification | HPLC retention time, NMR | HPLC/NMR |
| Loss on Drying | ≤ 0.5% | USP <731> |
| Residue on Ignition | ≤ 0.1% | USP <281> |
| Heavy Metals | ≤ 10 ppm | ICP-MS |
| Related Substances | Single impurity ≤ 0.5%; Total ≤ 1.0% | HPLC-UV |
| Residual Solvents | Meet USP <467> | GC |
| Purity (by Area %) | ≥ 99.0% | HPLC |
Purity: ≥ 98.0% (HPLC)
Source: Synthetic / High-purity production
Monthly capacity: 200+ kg
Lead time: 3–5 days (research samples), 10–15 days (bulk)
Documentation: COA, TDS, HPLC chromatogram, NMR (upon request)
Packaging options: 00g, 1kg, or as per customer request
📧 Email: info@lyvbio.com