Kojisäure-Dipalmitat

Kojisäure-Dipalmitat

Produktname Kojic Acid Dipalmitate
CAS-Nummer 79725-98-7
Molekülformel C₃₈H₆₆O₆
Molekulargewicht 618.93 g/mol
Aussehen Weißes bis cremefarbenes kristallines Pulver
Reinheit (HPLC) ≥ 98,01 TP3T
Schmelzpunkt 92–96°C
Säurezahl ≤ 5.0 mg KOH/g
Lagerung Kühl, trocken, verschlossen, lichtgeschützt
Haltbarkeit 36 Monate
Paket 100g, 500g, 1kg, 5kg, 25kg

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Kojic Acid Dipalmitate is a lipid-soluble derivative of kojic acid, created by esterifying kojic acid with palmitic acid. This structural modification addresses the two major limitations of free kojic acid: poor stability (oxidation, discoloration) und poor skin penetration (hydrophilic) .

Key differentiator: Kojic Acid Dipalmitate is the most stable and skin-bioavailable form of kojic acid, delivering superior brightening efficacy with no formulation discoloration (unlike free kojic acid which turns yellow/brown over time).

Why the market has shifted:

Parameter Kojic Acid Kojic Acid Dipalmitate
Löslichkeit Water-soluble Oil-soluble
Stability (color) Unstable (oxidizes yellow→brown) Stable (no discoloration)
Stability (heat) Degrades >50°C Stable >80°C
Skin penetration Poor (hydrophilic) Excellent (lipophilic)
Tyrosinase inhibition Potent (direct) Potent (after enzymatic hydrolysis)
Sustained release No (rapid) Yes (gradual release of active kojic acid)
Formulation pH Narrow (4–6) Broad (4–8)
Shelf life 12–18 months 36 Monate
Discoloration risk High (browning) Keine
Irritation potential Moderate (high dose) Low (gradual release)

Anwendungen

1. Skin Brightening & Hyperpigmentation (Primary Market)

Anwendung Typische Verwendung Kernaussagen
Melasma treatment creams 1–2% Reduces dark patches, even skin tone
Dark spot correctors 1–2% Fades age spots, sun spots, post-acne marks
Brightening serums 0.5–1.5% Illuminates, evens complexion
All-over body lotions 0.5–1% Even skin tone on arms, legs, décolletage

2. Anti-Aging & Luminous Skin

Anwendung Typische Verwendung Positioning
Luminous anti-aging creams 0.5–1.5% Brightening + wrinkle reduction
Night renewal treatments 1–2% Overnight brightening + cell turnover
Vitamin C combination serums 0.5–1% Multi-pathway brightening + antioxidant

3. Post-Inflammatory Hyperpigmentation (PIH)

Anwendung Typische Verwendung Target Consumer
Post-acne spot treatment 1–2% Acne-prone skin with residual marks
Post-procedure brightening 0.5–1% After laser, chemical peel (clinical use)
Pregnancy-safe brightening 0.5–1% Melasma / dark spots (safe alternative to hydroquinone)

Lieferant: LyvBio Co., Ltd.

LyvBio GmbH. is supplier of high-purity Kojic Acid Dipalmitate for the cosmetic and personal care industry.

Lieferkapazitäten:

  • Reinheit: ≥98,01 % TP3T (HPLC)

  • Monatliche Kapazität: 500+ kg

  • Großmengen: 100g – 5,000kg

  • Lieferzeit: 3–5 Tage (Muster), 10–15 Tage (Großmengen)

  • Dokumentation: COA, Sicherheitsdatenblatt (MSDS), Technisches Datenblatt (TDS), HPLC-Chromatogramm, Stabilitätsdaten

  • Verpackung: 100g, 500g, 1kg, 5kg, 25kg (foil bag or HDPE drum)

Kojic Acid Dipalmitate vs. Other Brightening Agents

Parameter Kojic Acid Dipalmitate Kojic Acid Hydroquinone Alpha-Arbutin Tranexamic Acid
Löslichkeit Oil Water Water Water Water
Stability Excellent Poor Good Good Excellent
Discoloration risk Keine Hoch Niedrig Keine Keine
Skin penetration Hoch Niedrig Hoch Mäßig Low-Moderate
Tyrosinase inhibition Potent (after hydrolysis) Potent Potent Mäßig None (different pathway)
Melasma efficacy Hoch Mäßig Very High Mäßig Hoch
Cytotoxicity Keine Niedrig Yes (at high conc.) Keine Keine
Regulatory (EU/US) Allowed Allowed Restricted (US), Banned (EU) Allowed Allowed
Clean beauty Good Mäßig Poor Good Good
Pregnancy safe Yes Yes No Yes Yes

buy Kojic acid dipalmitate

Häufig gestellte Fragen

Q: What is the difference between Kojic Acid and Kojic Acid Dipalmitate?
A: Kojic Acid Dipalmitate is the oil-soluble, stabilized ester of kojic acid. It is more stable (no discoloration), better penetrating, and easier to formulate than free kojic acid. It hydrolyzes on skin to release active kojic acid.

Q: Is Kojic Acid Dipalmitate more effective than Kojic Acid?
A: Yes, in finished formulations. Although free kojic acid has higher in vitro tyrosinase inhibition, its poor stability and penetration limit real-world efficacy. Kojic Acid Dipalmitate delivers more active kojic acid to melanocytes due to better penetration and stability.

Q: Does Kojic Acid Dipalmitate cause skin irritation?
A: No. It is non-irritating at recommended concentrations (0.5–2.0%). The gradual release of kojic acid reduces irritation potential compared to free kojic acid.

Q: Can Kojic Acid Dipalmitate be used during pregnancy?
A: Yes. Unlike hydroquinone, kojic acid derivatives have no known teratogenic risk. However, consult a physician before use.

Q: How should Kojic Acid Dipalmitate be stored?
A: Cool, dry, sealed, protected from light. Shelf life: 36 months.

Q: Is Kojic Acid Dipalmitate soluble in water?
A: No. It is oil-soluble. For water-based serums, use solubilizers or emulsify.

F: Wie hoch ist Ihre Mindestbestellmenge?
A: Sample orders: 100g–500g. Trial production: 1–5 kg. Commercial: Negotiable (25kg+ receives volume pricing). Lead time: 3–5 days (samples); 10–15 days (bulk).

Kontaktieren Sie LyvBio Co., Ltd.

📧 E-Mail: info@lyvbio.com
🌐 Website: https://www.lyvbio.com

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