Guanosine
| Product Name | Guanosine |
|---|---|
| CAS Number | 118-00-3 |
| Synonyms | Guanine riboside; 9-β-D-Ribofuranosylguanine; Guanine-9-β-D-ribofuranoside; Vernine; 2-Amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one |
| Molecular Formula | C10H13N5O5 |
| Molecular Weight | 283.24 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥98.0% |
| Melting Point | 250 °C (dec.) |
| Solubility | Sparingly soluble in water (0.75 g/L at 25 °C); practically insoluble in ethanol, acetone |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Storage | Store in a cool, dry place, protected from light and moisture |
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Synonyms: Guanine riboside, 9-β-D-Ribofuranosylguanine, Guanine-9-β-D-ribofuranoside, Vernine, 2-Amino-9-β-D-ribofuranosyl-9H-purine-6(1H)-one
Guanosine is a purine nucleoside composed of a guanine base linked to a ribose sugar via a β-N9-glycosidic bond. It occurs naturally in RNA and is produced industrially through fermentation or chemical synthesis, typically offered at ≥98% purity for pharmaceutical and biotech applications.
As a key intermediate in nucleotide metabolism, guanosine serves as a precursor to guanylic acid (GMP) and its derivatives, which are widely used as flavor enhancers and pharmaceutical actives. Its role in cellular signaling and energy transfer makes it a valuable building block for antiviral, anticancer, and cardiovascular research, as well as a standard in analytical laboratories.
| Parameter | Specification |
|---|---|
| Assay (HPLC) | ≥98.0% |
| Appearance | White to off-white crystalline powder |
| Identification | IR spectrum conforms to reference |
| Loss on Drying | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤10 ppm |
| Solubility | Sparingly soluble in water |
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