Phloretin

Synonyms: Phloretin, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one, Dihydronaringenin, Phloretol, Rhein (not to be confused with the anthraquinone), 2′,4,4′,6′-Tetrahydroxydihydrochalcone

Phloretin is a dihydrochalcone flavonoid found in apple leaves, roots, and especially in the peel of apples, pears, and other Rosaceae fruits. It is the aglycone of phlorizin, a glucoside that has been studied for decades in renal physiology. As a commercial ingredient, phloretin is produced via enzymatic hydrolysis of phlorizin or through synthetic routes, yielding a high-purity crystalline powder with a molecular weight of 274.27 g/mol (C15H14O5).

In the B2B space, phloretin is valued for its ability to inhibit glucose transporters (GLUT1, GLUT2, SGLT1/2) and for its antioxidant and anti-inflammatory properties. Formulators in the cosmetic and pharmaceutical industries use it as an active in skin-brightening, anti-aging, and barrier-repair products, while researchers employ it as a tool compound to study cellular glucose uptake and metabolic pathways. It is also explored as a natural preservative booster and stabilizer in certain food and beverage applications.

Product Highlights

• High purity: ≥98% by HPLC, suitable for cosmetic and research applications.
• Dual sourcing: Available from apple-derived and synthetic routes to meet cost and sustainability needs.
• Scalable supply: Consistent production capacity to support pilot to commercial quantities.
• Regulatory support: Documentation aligned with REACH, FDA, and cosmetic regulatory requirements.
• Quality assurance: Each lot tested for identity, purity, and residual solvents.
• Technical service: Formulation guidance and stability data available upon request.

Applications & Formulation Use

• Skin care: Used in serums and creams for its brightening and antioxidant effects, often combined with niacinamide or vitamin C.
• Pharmaceutical research: As a reference standard and active in studies of glucose transport and metabolic disorders.
• Food & beverage: Evaluated as a natural antioxidant and antimicrobial agent in functional foods.
• Nutraceuticals: Included in oral supplements targeting metabolic health and weight management.

Quality Specifications (QC Tests)

Bulk Supply & Ordering

• Packaging: 25 kg fiber drums with double polyethylene liners, or as requested.
• MOQ: 1 kg for stock items; 25 kg for custom packaging.
• Lead time: 3-5 business days for stock items.
• Documentation: COA, MSDS, TDS, and technical support provided.

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Phloretin?

Our MOQ is 1 kg for stock items. For custom packaging or larger quantities, please contact us to discuss your specific needs.

What is the delivery time?

For stock items, delivery is typically within 3-5 business days after order confirmation. We ship globally via express or air freight.

Can you provide a COA and samples?

Yes, we provide a COA for each lot. Samples are available upon request; please contact our sales team for arrangements.

What packaging options are available?

Standard packaging is 25 kg fiber drums with double polyethylene liners. We can also accommodate custom packaging sizes upon request.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.