Nitazoxanide

Nitazoxanide

Parameter Specification
Product Name Nitazoxanide
CAS Number 55981-09-4
Molecular Formula C12H9N3O5S
Molecular Weight 307.28 g/mol
Appearance Yellow crystalline powder
Assay (HPLC) ≥98.0%
Solubility Soluble in DMSO, slightly soluble in methanol, practically insoluble in water
Package 25 kg fiber drum

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Synonyms: Alinia, Nitazoxanide, 2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide, NTZ, 55981-09-4

Nitazoxanide has become a staple in anti-infective portfolios, especially as demand grows for broad-spectrum antiparasitic and antiviral candidates. Formulators value its well-documented activity against a range of protozoa and anaerobic bacteria, making it a versatile API for both human and veterinary applications.

Chemically, Nitazoxanide is a nitrothiazolyl-salicylamide derivative first developed in the 1980s. It is synthesized through acylation of 2-amino-5-nitrothiazole with acetylsalicylic acid. The molecule acts as a prodrug, with its active metabolite tizoxanide responsible for the primary pharmacological effects.

We supply Nitazoxanide with a minimum assay of 98.0% (HPLC), ensuring consistent potency for pharmaceutical compounding and research. Its favorable safety profile and broad-spectrum activity make it a reliable choice for manufacturers targeting enteric and systemic infections.

Product Overview & Composition

Nitazoxanide is a synthetic nitrothiazole derivative. It is practically insoluble in water but dissolves in polar aprotic solvents like DMSO. The compound is stable under normal storage conditions and is typically micronized to improve bioavailability in oral formulations.

Applications & Product Lines

  • Antiparasitic drugs: Used in treatments for Cryptosporidium, Giardia, and other protozoal infections.
  • Antiviral research: Investigated for activity against influenza, rotavirus, and hepatitis.
  • Veterinary medicine: Effective against gastrointestinal parasites in animals.
  • Compounding pharmacies: Incorporated into custom oral suspensions and capsules.

Quality Control Standards

Test Item Specification
Identification IR, UV conforms to standard
Loss on Drying ≤0.5%
Heavy Metals ≤20 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g
Organic Impurities ≤0.5% total

Bulk Packaging & Supply

  • Packaging: 25 kg fiber drum with double polyethylene liner
  • MOQ: 1 kg
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS provided with each shipment

Frequently Asked Questions

What is the minimum order quantity?

Our MOQ is 1 kg, but we can accommodate smaller quantities for research purposes upon request.

How long does delivery take?

For stock items, delivery is 3-5 business days from order confirmation.

Do you provide a COA and samples?

Yes, a COA is included with every order, and samples are available for evaluation.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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