PT-141/Bremelanotide

PT-141/Bremelanotide

Параметр Технические характеристики
Название продукта PT-141 / Bremelanotide
Номер CAS 189691-06-3
Молекулярная формула C50H68N14O10
Молекулярная масса 1025.2 g/mol
Внешний вид White to off-white lyophilized powder
Анализ (ВЭЖХ) ≥98.0%
Растворимость Soluble in water and physiological saline
Упаковка 1 g / 5 g / 10 g / 100 g

PT-141/Bremelanotide Structure

Синонимы: Bremelanotide, PT-141, PT 141, Bremelanotide Acetate, Palatinose, [Nle4, D-Phe7]-α-MSH, Melanotan II analog

PT-141, also known as Bremelanotide, is a synthetic cyclic heptapeptide supplied as a white to off-white lyophilized powder. It is manufactured through solid-phase peptide synthesis and purified by preparative HPLC to a minimum assay of 98.0%, making it suitable for research and development as well as for compounding pharmacies that require a well-characterized active.

The peptide is freely soluble in water and physiological saline, which simplifies reconstitution and allows formulators to prepare aqueous solutions without co-solvents. Its stability profile in lyophilized form supports long-term storage, and the powder is routinely handled in small-scale R&D settings as well as in pilot batches for nasal spray or injectable formulations.

Typical end uses include reference standards for analytical method development, in vitro receptor binding studies, and formulation trials for subcutaneous or intranasal delivery systems. The material is also used by contract research organizations as a comparator in melanocortin receptor research.

Applications & Formulation Use

PT-141 is primarily used in research and early-stage formulation work. It appears in lyophilized powder form for reconstitution into injectable solutions, and in nasal spray development where the peptide is dissolved in buffered saline with preservatives. Formulators also use it as a positive control in cell-based assays targeting melanocortin receptors.

Sourcing & Production

The peptide is produced by solid-phase peptide synthesis using Fmoc chemistry, followed by cleavage, cyclization, and reverse-phase HPLC purification. The final product is lyophilized and packaged under controlled conditions to maintain peptide integrity. Each batch is tested for identity and purity before release.

Bulk Supply & Documentation

  • Packaging: 1 g / 5 g / 10 g / 100 g in amber glass vials
  • MOQ: 1 g
  • Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
  • Documentation: COA and MSDS with every shipment, TDS on request

Contact & Ordering Information

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