Glycodeoxycholic Acid

Glycodeoxycholic Acid

Название продукта Glycodeoxycholic Acid
Номер CAS 360-65-6
Молекулярная формула C26H43NO5
Молекулярная масса 449.62 g/mol
Внешний вид Кристаллический порошок от белого до небелого цвета
Анализ (ВЭЖХ) ≥98.0%
Потери при сушке ≤1.0%
Остаток после прокаливания ≤0,11 TP3T
Тяжелые металлы ≤10 ppm
Растворимость Soluble in ethanol, methanol; slightly soluble in water
Хранение Store in a cool, dry place, protected from light

Glycodeoxycholic Acid Structure

Синонимы: Glycodeoxycholic acid, 3α,12α-Dihydroxy-5β-cholan-24-oylglycine, Glycodeoxycholate, N-[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]glycine, Deoxycholylglycine, 5β-Cholan-24-amide, N-(3α,12α-dihydroxy-24-oxo-5β-cholan-24-yl)glycine

Glycodeoxycholic Acid (CAS 360-65-6) is a conjugated secondary bile acid, formed in the liver by the amidation of deoxycholic acid with glycine. It is a key component of human bile and plays a critical role in the emulsification and absorption of dietary fats. This product is offered as a high-purity synthetic or semi-synthetic compound, with a typical assay of ≥98% (HPLC), making it suitable for advanced research and pharmaceutical applications.

In the life sciences and pharmaceutical sectors, Glycodeoxycholic Acid is primarily utilized as a reference standard, a biochemical tool, and a building block in the synthesis of more complex steroidal compounds. Its amphipathic nature makes it valuable in membrane protein studies and as a detergent in various biochemical assays. Additionally, it is explored for its potential in drug delivery systems and as a therapeutic agent in cholestatic liver diseases.

Основные особенности продукта

  • Высокая степень очистки: Manufactured under strict quality control to achieve ≥98% assay, ensuring reliable and reproducible results in sensitive applications.
  • Synthetic Origin: Produced via a controlled synthetic route, eliminating variability associated with animal-derived sources and ensuring consistent supply.
  • Поддержка в области нормативно-правового регулирования: Available with comprehensive documentation, including COA, MSDS, and TDS, to support regulatory submissions and quality audits.
  • Scalable Supply: Capable of fulfilling orders from grams to kilograms, with a current production capacity of up to 100 kg per month.
  • Индивидуальная упаковка: Offered in various packaging options to suit different storage and handling requirements, from research quantities to bulk orders.

Приложения

  • Reference Standards: Used in analytical laboratories as a reference standard for the identification and quantification of bile acids in biological samples.
  • Biochemical Research: Employed in studies of bile acid metabolism, lipid digestion, and membrane protein solubilization.
  • Pharmaceutical Intermediates: Serves as a starting material or intermediate in the synthesis of steroidal drugs and other bioactive compounds.
  • Drug Delivery: Investigated for its ability to enhance the permeability of drugs across biological membranes.
  • Diagnostics: Utilized in the development of diagnostic kits for liver function and bile acid malabsorption.

Технические характеристики

Параметр Технические характеристики
Внешний вид Кристаллический порошок от белого до небелого цвета
Анализ (ВЭЖХ) ≥98.0%
Потери при сушке ≤1.0%
Остаток после прокаливания ≤0,11 TP3T
Тяжелые металлы ≤10 ppm
Растворимость Soluble in ethanol, methanol; slightly soluble in water

Заказы и поставки

  • Упаковка: 1 g, 5 g, 25 g, 100 g, 1 kg, and bulk quantities. Custom packaging available upon request.
  • Минимальный объем заказа: 1 gram for standard packs; flexible for bulk orders.
  • Срок выполнения заказа: 3–5 рабочих дней (товары, имеющиеся в наличии)
  • Документация: COA, MSDS, TDS provided with each shipment. Additional documentation available upon request.

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