Tripeptide-10 Citrulline

Synonyms: Tripeptide-10 Citrulline, Lys-Cit-Trp, KCT, Lysine-Citrulline-Tryptophan, Tripeptide-10 Citrulline Acetate

Tripeptide-10 Citrulline is a synthetic tripeptide with the sequence lysine-citrulline-tryptophan, designed to support skin firmness and elasticity. It functions as a matrikine, a small signaling molecule that mimics fragments of extracellular matrix proteins to stimulate collagen synthesis and improve skin density. The peptide is typically supplied as a white powder, often in its acetate salt form for enhanced stability and solubility.

First introduced in the early 2000s, Tripeptide-10 Citrulline has become a staple in anti-aging formulations, particularly in premium serums and creams targeting mature skin. Its mechanism involves upregulating collagen I and III production while inhibiting matrix metalloproteinases (MMPs) that degrade collagen. This dual action helps to reduce the appearance of fine lines and wrinkles, and improves overall skin texture.

In the B2B market, Tripeptide-10 Citrulline is available with high purity (≥98% by HPLC) and is commonly used at concentrations ranging from 0.01% to 0.1% in cosmetic products. It is compatible with a wide range of formulation ingredients, including other peptides, antioxidants, and moisturizers. Our production follows strict quality control measures to ensure consistent performance and safety.

Function

• Collagen stimulation: Upregulates collagen I and III synthesis in fibroblasts.
• MMP inhibition: Reduces matrix metalloproteinase activity, protecting existing collagen.
• Skin firming: Improves skin elasticity and reduces sagging.
• Wrinkle reduction: Visibly diminishes fine lines and deep wrinkles.
• Barrier support: Enhances skin hydration and barrier function.

Source & Standardization

• Source: Synthetic peptide produced by solid-phase peptide synthesis (SPPS).
• Purity: ≥98% (HPLC).
• Form: White to off-white powder, acetate salt.
• Standardization: Each batch is tested for identity, purity, and residual solvents.
• Applications: Anti-aging serums, creams, lotions, and eye care products.

Specifications

Documentation & Supply

• Monthly capacity: 500 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 1 kg, 5 kg, 10 kg in aluminum foil bags or fiber drums
• Storage: Store in a cool, dry place away from direct sunlight

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com