Trigonelline Hydrochloride

Trigonelline Hydrochloride

Product Name Trigonelline Hydrochloride
CAS Number 6138-41-6
Molecular Formula C7H8ClNO2
Molecular Weight 173.60 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Solubility Soluble in water, slightly soluble in ethanol
Package 25 kg fiber drum with double polyethylene liner

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Trigonelline Hydrochloride Structure

Synonyms: N-Methylnicotinic acid hydrochloride, 1-Methylpyridinium-3-carboxylate hydrochloride, Coffearin hydrochloride, Trigonelline HCl, Nicotinic acid N-methylbetaine hydrochloride

Trigonelline hydrochloride is the hydrochloride salt of trigonelline (N-methylnicotinic acid), a naturally occurring alkaloid found in fenugreek seeds, coffee beans, and various plant species. Our product is a synthetic, high-purity grade (≥98% by HPLC) manufactured under strict quality control for pharmaceutical, nutraceutical, and research applications.

As a stable, water-soluble salt, trigonelline hydrochloride offers improved handling and formulation properties compared to the zwitterionic free base. It is widely utilized in metabolic health, neuroprotection, and antimicrobial studies, reflecting its diverse biological activities and growing commercial interest.

Product Highlights

  • High Purity: ≥98% assay (HPLC) ensures consistent performance in sensitive applications.
  • Reliable Supply: Produced in our FDA-registered facility with annual capacity exceeding 5 metric tons.
  • Regulatory Support: Compliant with EP/USP monographs where applicable; CEP and DMF available upon request.
  • Quality Assurance: Each batch is tested for identity, assay, residual solvents, and heavy metals.
  • Custom Packaging: Offered in 1 kg to 25 kg packaging to suit pilot to production scale.
  • Technical Service: Our team provides formulation and regulatory assistance for seamless integration.

Applications

  • Pharmaceutical intermediates for metabolic and neurological research.
  • Nutraceutical formulations targeting glucose metabolism and cognitive support.
  • Antimicrobial and antibacterial studies, particularly against oral pathogens.
  • Cosmetic ingredients for skin conditioning and anti-aging products.
  • Reference standard for analytical method development and quality control.

Specifications

Parameter Specification
Assay (HPLC) ≥98.0%
Appearance White to off-white crystalline powder
Identification IR, HPLC retention time conforms to standard
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Solubility Soluble in water, slightly soluble in ethanol

Ordering & Supply

  • Packaging: 1 kg, 5 kg, 25 kg fiber drums with double polyethylene liners.
  • MOQ: 1 kg for pilot scale; 25 kg for commercial orders.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and regulatory support provided with each shipment.

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