Thymalin

Thymalin

Parameter Specification
Product Name Thymalin
CAS Number 79621-14-0
Molecular Formula C33H54N8O10
Molecular Weight 722.8 g/mol
Appearance White to off-white lyophilized powder
Assay (HPLC) ≥98.0%
Solubility Soluble in water and aqueous buffers
Package 1 g / 10 g / 100 g

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Thymalin Structure

Synonyms: Thymalin, Thymic factor, Thymus peptide, Thymalin peptide, Thymic hormone peptide, Thymalin synthetic

Thymalin is a synthetic peptide preparation corresponding to a thymic extract fraction, supplied as a white to off-white lyophilized powder. It is manufactured by solid-phase peptide synthesis and purified to ≥98% by HPLC. Each lot is tested for identity and purity before release.

Buyers typically require the lyophilized powder in gram to kilogram quantities for use as a reference standard or as an active ingredient in injectable and lyophilized formulations. The material is freely soluble in water and aqueous buffers, which makes it straightforward to reconstitute and dilute in sterile manufacturing.

Formulators use Thymalin in parenteral preparations, lyophilized vials for reconstitution, and occasionally in research-grade peptide blends. It is not intended for oral solid dosage forms because of poor oral bioavailability.

Applications & Formulation Use

Thymalin is primarily used in injectable pharmaceutical preparations, including lyophilized vials and prefilled syringes. It also serves as a reference standard in analytical laboratories and as an active ingredient in research formulations for immunological studies. In sterile manufacturing, it is dissolved in water for injection or buffer, sterile-filtered, and aseptically filled.

Because the peptide is sensitive to heat and moisture, formulators handle it under controlled temperature and low-humidity conditions. It is compatible with common lyophilization excipients such as mannitol, sucrose, and trehalose, which are used to stabilize the powder during freeze-drying.

Sourcing & Production

Thymalin is produced by solid-phase peptide synthesis using Fmoc chemistry. The crude peptide is purified by preparative HPLC, then converted to the acetate salt and lyophilized. The final product is a white to off-white powder with a defined molecular weight of 722.8 g/mol and a purity of ≥98% by HPLC.

The synthesis and purification are carried out in a cGMP-compliant facility. Each batch is accompanied by a certificate of analysis that includes HPLC purity, mass spectrometry identity, and water content. The material is supplied in amber glass vials or bottles to protect from light.

Bulk Supply & Documentation

  • Packaging: 1 g / 10 g / 100 g in amber glass vials or bottles
  • MOQ: 1 g
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA and MSDS with every shipment, TDS on request

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