SS-31

SS-31

Parameter Specification
Product Name SS-31
CAS Number 736992-21-5
Molecular Formula C32H49N9O5
Molecular Weight 639.8 g/mol
Appearance White to off-white powder
Assay (HPLC) ≥98.0%
Solubility Soluble in water and physiological buffers
Package 1 mg, 5 mg, 10 mg, 50 mg, 100 mg (vial)

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SS-31 Structure

Synonyms: SS-31, Elamipretide, MTP-131, Bendavia, D-Arg-Dmt-Lys-Phe-NH2, Mitochondria-targeted peptide

SS-31 is a synthetic tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2, where Dmt stands for 2′,6′-dimethyltyrosine. It is manufactured via solid-phase peptide synthesis and supplied as a high-purity lyophilized powder, typically ≥98% by HPLC. The molecule is designed to target the inner mitochondrial membrane and is used in research and pharmaceutical development.

As a mitochondria-targeted peptide, SS-31 has attracted interest for its ability to interact with cardiolipin and stabilize mitochondrial cristae. It is explored in preclinical and clinical settings for conditions involving mitochondrial dysfunction, such as ischemia-reperfusion injury, heart failure, and certain rare diseases. Its well-defined mechanism and favorable safety profile make it a valuable tool for both research and formulation development.

Product Highlights

  • High purity: ≥98% by HPLC, ensuring reliable experimental results.
  • Scalable production: Available from gram to kilogram scale to support various stages of development.
  • Quality control: Each batch is tested for identity, purity, and residual solvents, with full documentation.
  • Regulatory support: Comprehensive regulatory files available for IND and NDA submissions.
  • Fast delivery: Stock items shipped within 3-5 business days.
  • Custom packaging: Offered in vials or bulk quantities to meet specific needs.

Applications & Formulation Use

  • Research: Studying mitochondrial function, oxidative stress, and cellular metabolism.
  • Pharmaceutical development: As an active ingredient in injectable formulations for clinical trials.
  • Formulation: Lyophilized powder for reconstitution; compatible with common excipients.
  • Analytical standards: Reference standard for HPLC and LC-MS methods.

Quality Specifications (QC Tests)

Test Item Specification
Identification Consistent with reference standard (HPLC, MS)
Loss on Drying ≤5.0%
Residue on Ignition ≤1.0%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g
Organic Impurities Any individual ≤1.0%; Total ≤2.0%

Bulk Supply & Ordering

  • Packaging: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg vials; bulk quantities available.
  • MOQ: 10 mg.
  • Lead time: 3-5 business days for stock items.
  • Documentation: COA, MSDS, TDS provided with each shipment.

Frequently Asked Questions

What is the minimum order quantity (MOQ) for SS-31?

The MOQ is 10 mg. For larger quantities, please contact our sales team for a quote.

What is the delivery time?

For stock items, delivery is 3-5 business days from order confirmation. We ship worldwide via express couriers.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is available for each batch. Samples can be provided upon request; please contact us for details.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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