Spermine Tetrahydrochloride (SPT)

Spermine Tetrahydrochloride (SPT)

Product Name Spermine Tetrahydrochloride (SPT)
CAS Number 306-67-2
Molecular Formula C10H26N4·4HCl
Molecular Weight 348.18 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Solubility Soluble in water, slightly soluble in ethanol
Package 1 kg, 5 kg, 25 kg fiber drums with inner polyethylene bags

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Spermine Tetrahydrochloride (SPT) Structure

Synonyms: Spermine tetrahydrochloride, N,N’-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride, 1,12-Diamino-4,9-diazadodecane tetrahydrochloride, Spermine 4HCl, SPT

Spermine tetrahydrochloride is the tetrahydrochloride salt of spermine, a naturally occurring polyamine found in all eukaryotic cells. It is produced through chemical synthesis and is commercially available as a high-purity white crystalline powder. As a salt form, it offers excellent water solubility and stability, making it a preferred choice for biochemical and pharmaceutical applications.

In the life sciences, spermine tetrahydrochloride is widely used as a crucial component in cell culture media, protein crystallization, and molecular biology protocols. It also serves as a key intermediate in the synthesis of various pharmaceutical compounds and is investigated for its potential in drug delivery systems and as a modulator of cellular processes.

Product Highlights

  • High Purity: ≥98.0% by HPLC, ensuring consistent performance in sensitive applications.
  • Reliable Supply: Produced in our ISO-certified facilities with scalable capacity to meet bulk demands.
  • Quality Documentation: Each batch comes with a comprehensive COA, MSDS, and TDS for full traceability.
  • Custom Packaging: Available in various pack sizes to suit laboratory and production needs.
  • Regulatory Support: Manufactured under cGMP guidelines, with support for regulatory filings as needed.
  • Fast Turnaround: Standard lead time of 5-7 business days for stock items.

Applications

  • Cell Culture: Supplement in media to promote cell growth and proliferation.
  • Protein Crystallization: Used as an additive to enhance crystal formation.
  • Molecular Biology: Employed in DNA precipitation and transfection protocols.
  • Pharmaceutical Synthesis: Intermediate for the production of APIs and drug candidates.
  • Research: Studied for its role in cellular signaling, autophagy, and aging.

Specifications

Parameter Specification
Assay (HPLC) ≥98.0%
Appearance White to off-white crystalline powder
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Solubility Soluble in water, slightly soluble in ethanol

Ordering & Supply

  • Packaging: 1 kg, 5 kg, 25 kg fiber drums with inner polyethylene bags.
  • MOQ: 1 kg for standard packs; flexible for bulk orders.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS provided with each shipment.

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