Sodium Ascorbyl Phosphate

Synonyms: SAP, Sodium L-ascorbyl-2-phosphate, Ascorbyl phosphate sodium salt, L-Ascorbic acid 2-phosphate sodium salt, 66170-10-3

Sodium Ascorbyl Phosphate (SAP) is a water-soluble derivative of vitamin C, engineered to overcome the stability limitations of L-ascorbic acid. The molecule carries a phosphate group at the C-2 position of the ascorbic acid ring, which blocks the primary oxidative degradation pathway and renders the compound resistant to air, light, and heat. This structural modification also imparts high water solubility, making SAP compatible with aqueous formulations across a broad pH range.

In the skin, SAP is dephosphorylated by endogenous phosphatases to release active ascorbic acid, which then participates in collagen synthesis, antioxidant defense, and melanin regulation. Because the parent molecule is delivered gradually, SAP provides sustained vitamin C activity without the irritation often associated with high-dose L-ascorbic acid. It is widely used in cosmetic and personal care products, particularly in anti-aging, brightening, and photoprotective formulations.

For B2B buyers, SAP offers a stable, easy-to-handle raw material that integrates smoothly into emulsions, serums, and gels. Its compatibility with other actives and its favorable safety profile make it a preferred choice for formulators targeting skin tone evenness and oxidative stress reduction.

Chemical Structure & Properties

Sodium ascorbyl phosphate is the trisodium salt of L-ascorbic acid 2-phosphate. The phosphate ester at C-2 prevents the molecule from undergoing the rapid lactone ring opening that degrades ascorbic acid in solution. The compound is a white to off-white powder, freely soluble in water (up to 50% w/v), and practically insoluble in ethanol. It remains stable in aqueous solutions at pH 5–8 and retains activity in the presence of common cosmetic preservatives.

Mechanism of Action

• Enzymatic dephosphorylation: Skin phosphatases cleave the phosphate group, releasing ascorbic acid intracellularly.
• Collagen synthesis: Ascorbic acid serves as a cofactor for prolyl and lysyl hydroxylases, supporting collagen cross-linking.
• Antioxidant defense: Scavenges reactive oxygen species and regenerates α-tocopherol from its radical form.
• Melanin regulation: Inhibits tyrosinase activity by interacting with copper at the enzyme active site, reducing hyperpigmentation.

Quality Specifications (QC Tests)

Supply & Documentation

• Capacity: 20 metric tons per month
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 25 kg fiber drum with double polyethylene liner; custom packaging upon request

Frequently Asked Questions

What is the minimum order quantity (MOQ)?

Our standard MOQ is 25 kg. For smaller trial quantities, we can accommodate 1 kg samples to support your formulation development.

How long does delivery take?

For stock items, delivery is 3-5 business days from order confirmation. We ship globally via air or sea freight, depending on your preference.

Can you provide a COA and samples?

Yes, a certificate of analysis (COA) is available for each batch. We also offer 1 kg samples for evaluation; sample dispatch is typically within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.