| Product Name | Eleutheroside E1 |
| CAS Number | 7374-79-0 |
| Molecular Formula | C₂₈H₃₆O₁₃ |
| Molecular Weight | 580.58 g/mol |
| Appearance | Brown yellow fine powder |
| Purity (HPLC) | ≥ 0.8% (extract grade) |
| Source | Eleutherococcus senticosus (Siberian ginseng) root |
| Solubility | Soluble in water, ethanol, DMSO |
| Loss on Drying | ≤ 2.0% |
| Heavy Metals | ≤ 10 ppm |
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Eleutheroside E1 is a bioactive phenylpropanoid glycoside and one of the key marker compounds found in Eleutherococcus senticosus (commonly known as Siberian ginseng), a woody shrub native to Northeast Asia. Unlike true ginseng (Panax ginseng), Siberian ginseng contains eleutherosides rather than ginsenosides—distinct chemical markers with adaptogenic properties.
Eleutheroside E1, along with Eleutherosides B and E, is used as a standardization marker for Siberian ginseng extracts, ensuring consistent adaptogenic activity. It is distinct from Eleutheroside E (CAS 39432-56-9)—note the “1” designation indicates a specific isomer or purified fraction.

Eleutherococcus senticosus (Rupr. & Maxim.) Maxim.)
| Compound | CAS No. | Role in Adaptogen Activity |
|---|---|---|
| Eleutheroside B (Syringin) | 118-34-3 | Anti-fatigue, immune modulation |
| Eleutheroside E | 39432-56-9 | Stress resistance, neuroprotection |
| Eleutheroside E1 | 7374-79-0 | Adaptogenic activity marker |
| Eleutheroside I | 114592-29-9 | Immune support |
Note: Eleutheroside E1 is a purified marker compound, primarily used for analytical reference, standardization, and research applications. For commercial nutraceutical formulations, standardized Siberian ginseng extract (containing a defined profile of eleutherosides) is typically used rather than the isolated single compound.
LyvBio Co., Ltd. supplies both pure Eleutheroside E1 (analytical grade) and standardized Siberian ginseng extract (commercial grade).

Siberian Ginseng extract 0.8%
| Parameter | Specification |
|---|---|
| Purity (HPLC) | ≥ 98.0% |
| Package | 100mg, 500mg, 1g, 5g, 10g |
| Lead time | 3–5 days (samples), 10–15 days (bulk) |
| Documentation | COA, MSDS, HPLC chromatogram, NMR (upon request) |
| Parameter | Specification |
|---|---|
| Eleutherosides (total HPLC) | ≥ 0.8% |
| Extract ratio | 4:1, 10:1, 20:1 (customizable) |
| Appearance | Brown to dark brown fine powder |
| Package | 1kg, 5kg, 10kg, 25kg |
| Lead time | 3–5 days (samples), 10–15 days (bulk) |
| Parameter | Specification | Test Method |
|---|---|---|
| Eleutherosides (total) | ≥ 1.0% | HPLC-UV |
| Eleutheroside B | ≥ 0.2% | HPLC-UV |
| Eleutheroside E | ≥ 0.4% | HPLC-UV |
| Extract ratio | 4:1, 10:1, 20:1 | Calculation |
| Appearance | Brown to dark brown powder | Visual |
| Loss on Drying | ≤ 5.0% | USP <731> |
| Heavy Metals | Pb ≤ 2 ppm; As ≤ 2 ppm; Cd ≤ 1 ppm; Hg ≤ 0.1 ppm | ICP-MS |
| Microbial | TPC ≤ 1,000 cfu/g; E. coli & Salmonella negative | USP <61> |
Q: What is the difference between Eleutheroside E1 and Eleutheroside E?
A: They are distinct compounds with different molecular weights and structures. Eleutheroside E (CAS 39432-56-9, MW 742.72) is a dimeric lignan glycoside. Eleutheroside E1 (CAS 7374-79-0, MW 580.58) is a different marker compound. Both are found in Siberian ginseng.
Q: Is Eleutheroside E1 the same as Siberian ginseng?
A: No. Siberian ginseng (Eleutherococcus senticosus) contains multiple bioactive compounds, including eleutherosides B, E, E1, I, and others. Eleutheroside E1 is just one marker compound.
Q: Should I use pure Eleutheroside E1 or standardized extract for my supplement?
A: For finished nutraceutical products, use standardized Siberian ginseng extract (e.g., ≥1% total eleutherosides). Pure Eleutheroside E1 is for analytical reference, research, or standardization purposes only.
Q: What is the typical eleutheroside content for extract standardization?
A: Common specifications: total eleutherosides ≥0.8–1.5% (HPLC), with Eleutheroside B ≥0.2% and Eleutheroside E ≥0.4%.
Q: Can Siberian ginseng be taken daily?
A: Yes, but cyclical use (e.g., 8 weeks on, 1–2 weeks off) is traditionally recommended for optimal adaptogenic effects and to prevent tolerance.
Q: What is your MOQ for pure Eleutheroside E1?
A: Research samples: 100mg–500mg. Bulk: 5g+. Lead time: 3–5 days (samples); 10–15 days (bulk).
Q: What is your MOQ for standardized Siberian ginseng extract?
A: Sample orders: 1kg. Trial production: 5–25 kg. Commercial: Negotiable. Lead time: 3–5 days (samples); 10–15 days (bulk).
Need analytical standards or standardized Siberian ginseng extract for your formulations?
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