Selamectin

Selamectin (CAS 220119-17-5) is a semi-synthetic macrocyclic lactone endectocide derived from the avermectin family, specifically engineered for systemic ectoparasite and endoparasite control in companion animals. Its unique monosaccharide oxime substitution at C13 enhances metabolic stability and water solubility, allowing for a single-dose, broad-spectrum efficacy profile. Supplied as a white to off-white crystalline powder with ≥98% HPLC purity, each batch is accompanied by COA, MSDS, and TDS.

This active pharmaceutical ingredient (API) is primarily used in veterinary formulations such as spot-on solutions and injectables for dogs and cats, targeting heartworm, fleas, ear mites, and certain intestinal nematodes. With a favorable safety margin and a mode of action distinct from other avermectins, selamectin remains a reliable choice for formulators developing year-round parasite prevention products.

Synonyms: Selamectin (USAN), Revolution, Stronghold, 4”-epi-acetylamino-4”-deoxyavermectin B1, UK-124114

Applications

• Veterinary spot-on and topical solutions for canine and feline parasite control
• Injectable formulations for heartworm prevention and treatment of ectoparasites
• Combination products targeting internal and external parasites in companion animals
• R&D and clinical trial supply for novel delivery systems

Quality & Documentation

Every batch is tested for assay (HPLC ≥98%), related substances, loss on drying (≤1.0%), and heavy metals (≤10 ppm). Full COA, MSDS, and TDS are available on request; stability data and impurity profiles can be provided for regulatory submissions.

Packaging & Supply

Standard packaging includes 1 kg, 5 kg, and 25 kg containers, with custom packing available upon request. In-stock items ship within 3–5 business days; MOQ is 1 kg. For pricing, samples, or bulk orders, contact our sales team.

Request For Quote

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