RU58841
| Product Name | RU58841 |
|---|---|
| CAS Number | 154992-24-2 |
| Other Names | PSK-3841; RU 58841; 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile |
| Molecular Formula | C13H10F3N3O2 |
| Molecular Weight | 297.23 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥98.0% |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤10 ppm |
| Solubility | Soluble in DMSO, ethanol; slightly soluble in water |
| Package | 1 kg, 5 kg, 25 kg drums |
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Synonyms: PSK-3841, RU 58841, 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile, RU-58841, 154992-24-2
RU58841 is a non-steroidal anti-androgen that has carved a niche in the research community for its topical activity against androgenetic alopecia and androgen-related skin conditions. Developed initially by Roussel Uclaf, this compound is a derivative of the topical anti-androgen flutamide, engineered to exert local effects without significant systemic absorption. It is available as a high-purity powder, typically ≥98% by HPLC, making it suitable for formulation and preclinical studies.
In the B2B arena, RU58841 is sought after by pharmaceutical and cosmetic ingredient buyers for its potential in hair care and dermatological products. Its mechanism involves competitive binding to the androgen receptor, thereby blocking dihydrotestosterone (DHT) from triggering follicle miniaturization. While not yet approved for clinical use, its profile continues to attract interest in the development of next-generation anti-hair loss solutions.
| Parameter | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥98.0% |
| Loss on Drying | ≤0.5% |
| Heavy Metals | ≤10 ppm |
| Solubility | Soluble in DMSO, ethanol; slightly soluble in water |
| Particle Size | NLT 98% through 80 mesh |
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