RU58841

RU58841

Product Name RU58841
CAS Number 154992-24-2
Other Names PSK-3841; RU 58841; 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile
Molecular Formula C13H10F3N3O2
Molecular Weight 297.23 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Solubility Soluble in DMSO, ethanol; slightly soluble in water
Package 1 kg, 5 kg, 25 kg drums

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RU58841 Structure

Synonyms: PSK-3841, RU 58841, 4-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)-2-(trifluoromethyl)benzonitrile, RU-58841, 154992-24-2

RU58841 is a non-steroidal anti-androgen that has carved a niche in the research community for its topical activity against androgenetic alopecia and androgen-related skin conditions. Developed initially by Roussel Uclaf, this compound is a derivative of the topical anti-androgen flutamide, engineered to exert local effects without significant systemic absorption. It is available as a high-purity powder, typically ≥98% by HPLC, making it suitable for formulation and preclinical studies.

In the B2B arena, RU58841 is sought after by pharmaceutical and cosmetic ingredient buyers for its potential in hair care and dermatological products. Its mechanism involves competitive binding to the androgen receptor, thereby blocking dihydrotestosterone (DHT) from triggering follicle miniaturization. While not yet approved for clinical use, its profile continues to attract interest in the development of next-generation anti-hair loss solutions.

Product Highlights

  • High purity: ≥98% by HPLC, ensuring consistent research outcomes.
  • Topical selectivity: Designed to act locally with minimal systemic exposure.
  • Scalable supply: Available in gram to kilogram quantities to support R&D through pilot production.
  • Quality documentation: Full COA, MSDS, and TDS provided with every batch.
  • Regulatory support: Assistance with documentation for research and formulation purposes.
  • Competitive pricing: Direct from manufacturer, eliminating middlemen costs.

Applications

  • Research on androgenetic alopecia and hair follicle biology.
  • Formulation development for topical anti-androgen products.
  • Preclinical studies on androgen receptor signaling pathways.
  • Investigational use in dermatological conditions like acne and hirsutism.

Specifications

Parameter Specification
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Solubility Soluble in DMSO, ethanol; slightly soluble in water
Particle Size NLT 98% through 80 mesh

Ordering & Supply

  • Packaging: 1 kg, 5 kg, and 25 kg drums with double-lined interior.
  • MOQ: 100 grams for research quantities; 1 kg for commercial orders.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and additional technical support available upon request.

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