Rotenone

Rotenone

Parameter Specification
Product Name Rotenone
CAS Number 83-79-4
Molecular Formula C23H22O6
Molecular Weight 394.42 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Solubility Soluble in acetone, chloroform, ethanol; practically insoluble in water
Package 25 kg fiber drum with inner polyethylene bag

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Rotenone Structure

Synonyms: Rotenone, Derris root extract, Tubatoxin, Nicouline, Derris elliptica extract, Lonchocarpus species extract, Cube root extract.

Rotenone is a naturally occurring isoflavone derivative that functions as a broad-spectrum insecticide and piscicide. It is extracted from the roots of several tropical legumes, including Derris elliptica, Lonchocarpus utilis, and Tephrosia vogelii. Historically, these plants were used by indigenous cultures for fishing and pest control, and rotenone remains an important tool in agriculture and aquaculture.

As a mitochondrial complex I inhibitor, rotenone disrupts cellular respiration, leading to insect mortality. Its selectivity toward insects and fish over mammals is due to differences in metabolic pathways and absorption. The compound is valued for its rapid degradation in the environment, making it a preferred choice for organic farming and integrated pest management.

Commercial rotenone is standardized to high purity, typically ≥98% by HPLC, and is available as a crystalline powder. It is used in formulations for crop protection, fish management, and as a reference standard in research.

Function & Mechanism

  • Insecticidal activity: Inhibits mitochondrial electron transport chain, causing energy depletion and death.
  • Piscicidal activity: Rapidly absorbed through fish gills, effective for population control.
  • Selective toxicity: Low mammalian toxicity due to poor absorption and rapid metabolism.
  • Environmental fate: Breaks down quickly in sunlight and soil, reducing persistence.
  • Mode of action: Acts as a stomach and contact poison, affecting both chewing and sucking insects.

Source & Standardization

  • Source: Roots of Derris elliptica, Lonchocarpus spp., and related legumes.
  • Extraction: Solvent extraction followed by purification and crystallization.
  • Standardization: ≥98.0% rotenone (HPLC).
  • Forms: White to off-white crystalline powder.
  • Applications: Agricultural insecticides, fish management, research, and organic farming.

Quality Specifications (QC Tests)

Test Item Specification
Identification IR spectrum conforms to reference
Loss on Drying ≤1.0%
Residue on Ignition ≤0.5%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent
Organic Impurities Sum of related substances ≤2.0%
Residual Solvents Meets ICH Q3C guidelines

Bulk Supply & Documentation

  • Monthly capacity: 5 metric tons
  • Lead time: 3-5 business days
  • Documentation: COA, MSDS, TDS available upon request
  • Packaging: 25 kg fiber drums with inner polyethylene bags

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Rotenone?

Our standard MOQ is 1 kg. For larger quantities, please contact our sales team for pricing and availability.

What is the delivery time?

For stock items, delivery is 3-5 business days from order confirmation.

Do you provide samples and COA?

Yes, we provide samples for quality evaluation and a COA for each batch. Please request when placing an order.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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