Puerarin

Synonyms: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one 8-β-D-glucopyranoside; 8-C-Glucosyl-7,4′-dihydroxyisoflavone; Puerarin; Daidzein 8-C-glucoside; Kakonein; 3681-99-0

Puerarin is a naturally occurring isoflavone C-glucoside found primarily in the roots of Pueraria lobata (kudzu), a plant deeply rooted in Traditional Chinese Medicine. For centuries, kudzu root has been used to address cardiovascular and neurological conditions, and modern research has identified puerarin as its principal bioactive constituent. Unlike many flavonoids, puerarin possesses a unique C-glycosidic linkage, which confers greater stability and distinct pharmacological properties.

As a pure compound, puerarin is isolated and purified to high standards, typically achieving ≥98% purity by HPLC. It appears as a white to off-white crystalline powder, sparingly soluble in water but readily soluble in polar organic solvents like ethanol and methanol. This solubility profile makes it suitable for a range of formulation approaches, from oral solid dosage forms to injectable preparations in clinical settings.

In the B2B pharmaceutical and nutraceutical space, puerarin is valued for its vasodilatory, antioxidant, and neuroprotective effects. It is a key ingredient in products targeting cardiovascular health, cognitive function, and metabolic syndrome. Its well-documented safety profile and synergistic potential with other botanicals make it a versatile component for formulators.

Function & Mechanism

• Vasodilation: Puerarin promotes nitric oxide-mediated relaxation of blood vessels, improving circulation.
• Antioxidant activity: Scavenges free radicals and upregulates endogenous antioxidant enzymes.
• Cardioprotection: Reduces myocardial ischemia-reperfusion injury and protects endothelial function.
• Neuroprotection: Inhibits neuroinflammation and supports neuronal survival in ischemic models.
• Metabolic modulation: Enhances insulin sensitivity and lipid metabolism in preclinical studies.

Source & Standardization

• Source: Roots of Pueraria lobata (Wild.) Ohwi
• Extraction: Hydroalcoholic extraction followed by chromatographic purification
• Standardization: ≥98.0% puerarin (HPLC)
• Forms: White to off-white crystalline powder
• Applications: Pharmaceuticals, nutraceuticals, functional foods, research

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Monthly capacity: 5 metric tons
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: 25 kg fiber drum with double polyethylene liner, or customized packaging

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Puerarin?

Our standard MOQ is 1 kg. For larger quantities, we offer competitive pricing and flexible packaging options.

What is the delivery time?

For stock items, delivery is typically 3-5 business days after order confirmation. We maintain ample inventory to ensure prompt shipment.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, we provide a COA for each batch. Samples are available upon request for quality evaluation; sample dispatch is usually arranged within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.