Pterostilbene

Pterostilbene

Product Name Pterostilbene
CAS Number 537-42-8
Other Names 3,5-Dimethoxy-4'-hydroxy-trans-stilbene; trans-Pterostilbene
Molecular Formula C16H16O3
Molecular Weight 256.30 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Solubility Soluble in ethanol, DMSO, and other organic solvents; practically insoluble in water
Particle Size 98% through 80 mesh
Package 25 kg fiber drum with double polyethylene liner

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Pterostilbene Structure

Synonyms: Pterostilbene, 3,5-Dimethoxy-4′-hydroxy-trans-stilbene, trans-Pterostilbene, 4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenol

Pterostilbene has moved from a research curiosity to a staple in the premium supplement aisle. Often called the ‘better resveratrol’ by formulators, it is attracting attention for its improved oral bioavailability and metabolic stability. Brands are incorporating it into anti-aging, cognitive support, and metabolic health products, where it competes directly with resveratrol but at lower doses.

Chemically, pterostilbene is a stilbenoid natural product, structurally related to resveratrol but with two methoxy groups replacing hydroxyl groups. It occurs naturally in small amounts in blueberries, grapes, and Pterocarpus marsupium, though commercial quantities are produced via synthetic routes to ensure purity and supply consistency. The compound’s lipophilic nature allows it to cross cell membranes more readily than its hydroxylated cousin.

LyvBio supplies pterostilbene with a minimum assay of 98% by HPLC, verified by an independent third-party laboratory. Each batch is tested for residual solvents, heavy metals, and microbial contamination to meet pharmaceutical and nutraceutical standards. Our material is manufactured under cGMP conditions and comes with a complete documentation package for regulatory submissions.

Product Overview & Composition

Pterostilbene is a single, well-defined chemical entity, not a botanical extract. It is produced through a multi-step synthesis that yields a high-purity crystalline solid. The compound is characterized by its trans configuration, which is the biologically active form. We control the synthesis to minimize cis-isomer content, typically below 0.5%.

The material is stable under normal storage conditions. It should be kept in a cool, dry place away from direct sunlight and oxidizing agents. Our standard packaging includes an aluminum foil bag inside a fiber drum to protect against moisture and light.

Key Applications

  • Dietary Supplements: Used in capsules and tablets for antioxidant and anti-aging support, often combined with resveratrol or NAD+ precursors.
  • Functional Foods & Beverages: Incorporated into fortified drinks and snacks targeting metabolic wellness.
  • Cosmeceuticals: Added to skincare formulations for its potential anti-inflammatory and antioxidant effects.
  • Research: Employed in preclinical and clinical studies investigating its effects on aging, cognition, and glucose metabolism.
  • Nutraceutical Blends: Used as a key ingredient in synergistic blends with other polyphenols.

Quality & Standards

Parameter Specification
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Residual Solvents Meets ICH Q3C limits
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

Packaging & Supply

  • Packaging: 25 kg fiber drum with double polyethylene liner, or as requested.
  • MOQ: 1 kg for trial orders; 25 kg for bulk production.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and regulatory support available upon request.

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