povidone iodine

povidone iodine

Parameter Specification
Product Name Povidone Iodine
CAS Number 25655-41-8
Molecular Formula (C6H9NO)n·xI2
Appearance Brownish-red to reddish-brown powder
Assay (HPLC) 10% available iodine
Solubility Soluble in water and ethanol
Package 25 kg fiber drum with double polyethylene liner
Specification 10%

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Synonyms: PVP-I, Polyvinylpyrrolidone-iodine complex, Povidone-iodine, Betadine, Iodopovidone, PVPI

Povidone iodine has become a staple in antiseptic formulations across pharmaceutical, medical, and personal care sectors. Its broad-spectrum antimicrobial activity and excellent safety profile make it a preferred choice for wound care, surgical scrubs, and infection control products. The global demand for effective disinfectants continues to rise, especially in healthcare settings and consumer hygiene products.

Chemically, povidone iodine is a stable complex of iodine with polyvinylpyrrolidone (PVP). This complexation improves solubility and reduces irritation compared to free iodine, while maintaining a sustained release of active iodine. It is typically produced by reacting PVP with elemental iodine in an aqueous medium, yielding a water-soluble powder with a characteristic brownish-red color.

LyvBio supplies povidone iodine at 10% available iodine, a standard concentration that balances efficacy and stability. Our material is manufactured under cGMP conditions and is suitable for a wide range of applications, from topical antiseptics to industrial disinfectants. The product is available in bulk quantities and comes with comprehensive documentation to support regulatory submissions.

Product Overview & Composition

Povidone iodine is composed of approximately 10% available iodine bound to a polyvinylpyrrolidone carrier. The PVP backbone enhances the solubility of iodine and allows for a gradual release of free iodine, which is responsible for the antimicrobial action. This formulation minimizes the staining and irritation associated with traditional iodine solutions.

The complex is stable under normal storage conditions and retains its activity over time. It is compatible with a variety of excipients and can be incorporated into creams, ointments, solutions, and sprays. The 10% concentration is widely used in both pharmaceutical and cosmetic products.

Applications & Product Lines

  • Antiseptic solutions: Used for skin disinfection before surgery and for wound cleaning.
  • Ointments and creams: Formulated for topical treatment of minor cuts, burns, and infections.
  • Surgical scrubs: Incorporated into hand washes and preoperative skin preparations.
  • Oral care products: Added to mouthwashes and gargles for its antimicrobial properties.
  • Veterinary products: Used in animal wound care and disinfection.
  • Industrial disinfectants: Applied in water treatment and surface sanitization.

Quality Control Standards

Test Item Specification
Identification IR spectrum conforms to reference
Loss on Drying ≤ 8.0%
Heavy Metals ≤ 20 ppm
Microbial Limits Total aerobic count ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g; E. coli absent
Organic Impurities Complies with EP/USP

Bulk Packaging & Supply

  • Packaging: 25 kg fiber drum with double polyethylene liner, or as per customer request.
  • MOQ: 25 kg
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.

Frequently Asked Questions

What is the minimum order quantity (MOQ) for povidone iodine?

Our standard MOQ is 25 kg. For smaller quantities, please contact us to discuss your specific needs.

What is the delivery time?

For stock items, delivery typically takes 3-5 business days after order confirmation.

Can you provide a COA and samples?

Yes, we provide a COA for each batch. Samples are available upon request, usually shipped within 1-2 days.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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