Palmitoyl Hexapeptide-12

Synonyms: Palmitoyl hexapeptide-12, N-palmitoyl-hexapeptide-12, Palmitoyl oligopeptide, Anti-wrinkle peptide, Collagen-stimulating peptide, Matrixyl-like peptide

Palmitoyl Hexapeptide-12 is a synthetic peptide designed for cosmetic applications, particularly in anti-aging formulations. Its sequence mimics a fragment of collagen, the key structural protein in skin, and is conjugated to a palmitic acid chain to enhance skin penetration and stability. This peptide is widely used in topical skincare products to reduce the appearance of fine lines and wrinkles, improve skin firmness, and promote a more youthful complexion.

The palmitoyl moiety not only anchors the peptide to the skin’s lipid bilayer but also increases its lipophilicity, ensuring efficient delivery to the dermal layers where collagen synthesis occurs. Palmitoyl Hexapeptide-12 is known for its ability to stimulate fibroblasts, the cells responsible for producing collagen and elastin, thereby supporting the skin’s natural repair processes. Unlike retinol or other harsh actives, this peptide offers a gentle yet effective approach to skin rejuvenation, making it suitable for all skin types, including sensitive skin.

Function

• Collagen synthesis stimulation: Promotes the production of collagen types I and III, improving skin elasticity and firmness.
• Anti-wrinkle activity: Reduces the depth and volume of fine lines and wrinkles.
• Skin barrier support: Enhances the skin’s natural repair mechanisms, strengthening the epidermal barrier.
• Antioxidant protection: Scavenges free radicals and reduces oxidative stress, preventing premature aging.
• Moisture retention: Helps maintain skin hydration by supporting the extracellular matrix.

Source & Standardization

• Source: Synthetic peptide produced via solid-phase peptide synthesis (SPPS)
• Extraction: Not applicable (synthetic product)
• Standardization: ≥98.0% peptide content by HPLC
• Forms: White to off-white powder, free of preservatives
• Applications: Anti-aging cosmetics, serums, creams, lotions, and research studies

Specifications

Documentation & Supply

• Monthly capacity: 5kg
• Lead time: 3-5 working days after order confirmation
• Documentation: COA, MSDs and allergen statement available
• Packaging: Moq 5g

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd. — Email: info@lyvbio.com