Nicotine

Nicotine

Parameter Specification
Product Name Nicotine
CAS Number 54-11-5
Molecular Formula C10H14N2
Molecular Weight 162.23 g/mol
Appearance Colorless to pale yellow liquid
Assay (HPLC) ≥99.0%
Solubility Miscible with water, ethanol, chloroform
Package 25 kg drum, 200 kg drum

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Nicotine Structure

Synonyms: (S)-3-(1-Methylpyrrolidin-2-yl)pyridine, Nicotine, (S)-Nicotine, L-Nicotine, β-Pyridyl-α-N-methylpyrrolidine, Nicotine alkaloid

Nicotine is a naturally occurring alkaloid found primarily in the tobacco plant, Nicotiana tabacum, and to a lesser extent in other Solanaceae species. It is a chiral molecule, with the (S)-enantiomer being the predominant and biologically active form. This product is a high-purity synthetic or extracted grade, standardized to ≥99.0% (HPLC), suitable for pharmaceutical, nutraceutical, and research applications.

As a nicotinic acetylcholine receptor agonist, nicotine is widely studied for its effects on cognitive function, mood, and metabolism. It serves as a key intermediate in the synthesis of nicotine replacement therapies (NRTs) and is used in smoking cessation products, insecticides, and as a reference standard in analytical laboratories.

Product Highlights

  • High Purity: ≥99.0% by HPLC, ensuring consistent performance.
  • Dual Sourcing: Available from both synthetic and natural extraction routes.
  • Regulatory Support: Manufactured under cGMP conditions; DMF and CEP available upon request.
  • Large-scale Supply: Annual capacity exceeding 100 metric tons.
  • Custom Packaging: Options from small aliquots to 200 kg drums.
  • Fast Turnaround: Stock items shipped within 3-5 business days.

Applications & Formulation Use

  • Nicotine replacement therapies (patches, gums, lozenges, inhalers).
  • Pharmaceutical intermediates and API synthesis.
  • Research on nicotinic receptors and neurological pathways.
  • Insecticidal formulations for agricultural use.
  • Analytical reference standards and quality control.

Quality Specifications (QC Tests)

Test Item Specification
Identification IR, HPLC retention time conforms to standard
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent
Organic Impurities Any individual ≤0.1%; Total ≤0.5%

Bulk Supply & Ordering

  • Packaging: 25 kg or 200 kg drums, or customized packaging upon request.
  • MOQ: 1 kg for standard packaging; flexible for trial orders.
  • Lead time: 3-5 business days for stock items.
  • Documentation: COA, MSDS, TDS, and regulatory support provided.

Frequently Asked Questions

What is the minimum order quantity (MOQ)?

Our standard MOQ is 1 kg. For trial orders or specific research needs, we can accommodate smaller quantities. Please contact us for details.

What is the delivery time?

For stock items, delivery is 3-5 business days from order confirmation. Custom or large-volume orders may require additional time, which will be communicated upon order placement.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is available for each batch. Samples can be provided for evaluation; please specify your requirements when contacting us.

What are the packaging options?

We offer 25 kg and 200 kg drums as standard. Custom packaging is available to meet your specific needs.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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Our Address

Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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