methyl hesperidin

Methyl hesperidin is a semi-synthetic flavonoid derived from hesperidin, the predominant flavanone glycoside in citrus peels. Methylation of the phenolic hydroxyl groups enhances its lipophilicity and membrane permeability, which translates into better bioavailability and more consistent performance in finished formulations. We supply it as a free-flowing off-white to light yellow powder, assayed by HPLC at ≥95%, with full documentation for regulatory and quality compliance.

This ingredient has carved out a niche in oral care, cosmetic, and nutraceutical applications. Its improved solubility profile—compared to parent hesperidin—makes it a practical choice for clear liquid products and high-load capsules. We’ve worked with formulators across Europe and North America who value its stability in challenging matrices and the reproducible batch-to-batch consistency we deliver.

Synonyms: Hesperidin methyl chalcone, methylated hesperidin, 4′-O-methylhesperidin, HMC, methyl hesperidin complex

Applications

• Oral care: anti-inflammatory and capillary-protective mouthwashes, toothpastes
• Cosmetic: anti-aging serums, eye creams, and UV-stress recovery products
• Dietary supplements: vascular health and microcirculation support capsules
• Pharmaceutical R&D: topical and oral dosage form development

Quality & Documentation

Every batch is tested for assay (HPLC ≥95%), loss on drying (≤5.0%), and heavy metals (≤10 ppm). Microbial limits meet USP/EP requirements. We provide a full COA, MSDS, and TDS per shipment; stability data and residual solvent profiles are available on request for qualification.

Packaging & Supply

Standard packaging is 1 kg, 5 kg, and 25 kg fiber drums with double PE liners. Custom packing—from 100 g lab samples to 100 kg bulk—is routine. In-stock items ship within 3–5 business days; MOQ is 1 kg. For pricing, samples, or technical questions, contact our sales team.

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd. — Email: info@lyvbio.com