Menthoxypropanediol

Menthoxypropanediol

Product Name Menthoxypropanediol
CAS Number 87061-04-9
Synonyms 3-[(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl]oxypropane-1,2-diol; Menthoxypropanediol; MPD; Cooling Agent MPD
Molecular Formula C13H26O3
Molecular Weight 230.34 g/mol
Appearance Colorless to pale yellow clear liquid or low-melting solid
Assay (GC) ≥98.0%
Specific Rotation [α]D20 -50° to -60° (neat)
Refractive Index 1.4600 - 1.4700 (20°C)
Solubility Soluble in ethanol, propylene glycol, and oils; slightly soluble in water
Package 25 kg net in plastic drum, or as per customer request

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Menthoxypropanediol Structure

Synonyms: 3-[(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl]oxypropane-1,2-diol; Menthoxypropanediol; MPD; Cooling Agent MPD

Menthoxypropanediol is a synthetic cooling agent derived from menthol, belonging to the class of menthol glycerol ethers. It is produced through a reaction between L-menthol and glycidol, yielding a colorless to pale yellow liquid with a characteristic mild minty odor. The compound is widely used in personal care, food, and pharmaceutical applications where a long-lasting, smooth cooling effect is desired without the sharp, burning sensation associated with menthol.

As a high-purity ingredient (≥98% GC), Menthoxypropanediol is particularly valued for its ability to provide a sustained cooling sensation that develops slowly and lingers, making it ideal for products requiring extended sensory performance. Its excellent solubility profile in both oil- and water-based systems allows formulators to incorporate it into a wide range of formulations, from leave-on skin care to oral care and confectionery.

Product Highlights

  • High Purity: ≥98% assay (GC), ensuring consistent performance and minimal impurities.
  • Long-Lasting Cooling: Provides a gradual onset and prolonged cooling effect compared to menthol.
  • Low Irritation: Non-irritating to skin and mucous membranes at recommended use levels.
  • Versatile Solubility: Compatible with both aqueous and oily systems, facilitating easy incorporation.
  • Regulatory Compliance: Manufactured under cGMP, compliant with REACH and FDA regulations for intended uses.
  • Reliable Supply: Stable production capacity with short lead times and comprehensive documentation.

Applications

  • Oral care products: toothpastes, mouthwashes, and breath fresheners for a refreshing, lingering coolness.
  • Confectionery and chewing gum: provides a smooth, long-lasting cooling sensation without bitterness.
  • Personal care: skin care lotions, after-sun products, and shaving creams for a soothing effect.
  • Pharmaceuticals: topical analgesics and anti-itch creams where a cooling effect is beneficial.
  • Flavor and fragrance: used as a cooling modulator in various flavor blends.

Specifications

Parameter Specification
Appearance Colorless to pale yellow clear liquid
Assay (GC) ≥98.0%
Specific Rotation -50° to -60° (neat)
Refractive Index 1.4600 – 1.4700 (20°C)
Heavy Metals ≤10 ppm
Loss on Drying ≤0.5%

Ordering & Supply

  • Packaging: 25 kg net in plastic drum, or as per customer request.
  • MOQ: 25 kg.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.

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