| Product Name | Glabridin |
|---|---|
| CAS Number | 59870-68-7 |
| Molecular Formula | C₂₀H₂₀O₄ |
| Molecular Weight | 324.37 g/mol |
| EINECS Number | 611-908-7 |
| Appearance | Brownish-red to off-white powder (varies by purity) |
| Assay (HPLC) | 40% or 90% (per grade) |
| Solubility | Soluble in DMSO (5 mg/mL, clear with heating) |
| Loss on Drying | ≤ 5.0% |
| Residue on Ignition | ≤ 5.0% |
| Heavy Metals | ≤ 10 ppm |
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Synonyms: Glabridin, Glycyrrhiza glabra L. extract, Licorice flavonoid oil, Glabridin 40%, Glabridin 90%, Glabridine, 4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol.
Glabridin is the main active isoflavonoid derived from the roots of licorice (Glycyrrhiza glabra L.).
It is a lipophilic compound known for its skin-brightening and anti-inflammatory properties. Unlike other licorice extracts that contain glycyrrhizic acid, Glabridin is non‑steroidal and has a stronger affinity for melanin synthesis pathways.
In cosmetic applications, Glabridin is valued for its ability to inhibit tyrosinase activity and reduce melanin production, making it a key ingredient in skin brightening and dark spot correction formulations. It also exhibits antioxidant and anti-inflammatory effects, supporting skin protection and soothing irritated skin.
licorice extract Glabridin
Skin brightening: Inhibits tyrosinase, reducing melanin production and promoting even skin tone.
Antioxidant: Scavenges free radicals, protects against oxidative stress.
Anti-inflammatory: Reduces redness and irritation by modulating inflammatory pathways.
UV protection: Provides mild photoprotective effects by reducing UV-induced damage.
Anti-aging: Supports collagen preservation and skin elasticity.
Source: Licorice root (Glycyrrhiza glabra L.)
Standardization: 40% or 90% Glabridin (HPLC)
| Grade | Glabridin Content (HPLC) | Appearance | Typical Use |
|---|---|---|---|
| 40% | ≥ 40.0% | Brownish-red powder or white | General skin brightening products, cost‑effective |
| 90% | ≥ 90.0% | Off‑white to light beige powder | Premium brightening formulations, research |
Monthly capacity: 500+ kg (40%), 100+ kg (90%)
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA, MSDS, TDS, HPLC chromatogram, stability data
Packaging: 1 kg, 5 kg, 10 kg, 25 kg
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