Lemairamin (WGX-50)

Synonyms: N-trans-Feruloyltyramine, (E)-N-Feruloyltyramine, trans-Feruloyltyramine, WGX-50, N-(4-Hydroxyphenethyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide

Lemairamin (WGX-50) is a naturally occurring phenolic amide isolated from the roots of Lycium chinense Mill. and other Solanaceae plants. It is a cinnamamide derivative formed by the condensation of ferulic acid with tyramine, and it typically appears as a white to off-white crystalline powder. For research and pharmaceutical development, LyvBio supplies high-purity Lemairamin (≥98% by HPLC), ensuring consistent quality for advanced studies.

With its unique mechanism involving the activation of transient receptor potential vanilloid 1 (TRPV1) and modulation of neurotrophic factors, Lemairamin has gained attention as a promising candidate for cognitive enhancement and neuroprotection. It is widely used in preclinical research targeting Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative conditions, as well as in studies on pain and inflammation.

Product Highlights

• High Purity: ≥98% by HPLC, meeting rigorous research and pharmaceutical development standards.
• Natural Origin: Isolated from Lycium chinense and other natural sources, ensuring structural authenticity.
• Scalable Supply: Available in gram to kilogram quantities, with commercial-scale production capacity.
• Regulatory Support: Full documentation including COA, MSDS, and TDS for regulatory submissions.
• Custom Solutions: Custom packaging and labeling available to meet specific client requirements.
• Quality Assurance: Manufactured under GMP-like conditions with strict quality control at every batch.

Applications

• Neurodegenerative Disease Research: Investigated for its potential to inhibit amyloid-beta aggregation and tau hyperphosphorylation.
• Cognitive Function Studies: Used in models of memory impairment and cognitive decline.
• Pain & Inflammation Research: Explored as a TRPV1 agonist with analgesic properties.
• Nutraceutical Development: Incorporated into formulations targeting brain health and anti-aging.
• Pharmacological Tool: Serves as a reference standard for analytical method development.

Specifications

Ordering & Supply

• Packaging: 1 kg, 5 kg, or 25 kg fiber drums with double LDPE liners; custom packaging available.
• MOQ: 100 grams (for research quantities); flexible for larger orders.
• Lead time: 3-5 business days for stock items; 2-3 weeks for custom orders.
• Documentation: COA, MSDS, TDS, and additional regulatory support upon request.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com