L-Selenomethionine

L-Selenomethionine

Product Name L-Selenomethionine
CAS Number 3211-76-5
Synonyms (S)-2-Amino-4-(methylseleno)butyric acid; L-Selenomethionine; Se-Methyl-L-selenocysteine
Molecular Formula C5H11NO2Se
Molecular Weight 196.11 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥98.0%
Specific Rotation [α]D20 +18° to +22° (c=1, H2O)
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Arsenic ≤2 ppm
Solubility Soluble in water, slightly soluble in ethanol
Particle Size 98% pass 80 mesh
Package 25 kg fiber drum with double polyethylene bags

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L-Selenomethionine Structure

Synonyms: (S)-2-Amino-4-(methylseleno)butyric acid; L-Selenomethionine; Se-Methyl-L-selenocysteine; L-Selenomethionine.

L-Selenomethionine has become a preferred selenium source in premium dietary supplements and clinical nutrition, driven by its superior bioavailability and ability to support a wide range of physiological functions. As an essential trace element, selenium plays a critical role in antioxidant defense, thyroid hormone metabolism, and immune function. The L-isomer is the natural form found in food and is more efficiently utilized by the body compared to inorganic selenium salts.

L-Selenomethionine is a selenoamino acid where selenium replaces the sulfur atom in methionine. It is naturally present in Brazil nuts, grains, and certain vegetables, but for commercial use, it is produced through chemical synthesis or fermentation. The compound is highly stable and water-soluble, making it ideal for various formulations.

Our L-Selenomethionine is standardized to ≥98.0% purity (HPLC), ensuring consistent potency and reliability. It is widely used in nutraceuticals, functional foods, and pharmaceutical applications targeting selenium supplementation, antioxidant support, and thyroid health.

Product Overview & Composition

L-Selenomethionine is a white to off-white crystalline powder with a molecular formula of C5H11NO2Se and a molecular weight of 196.11 g/mol. It is the organic form of selenium, where selenium is covalently bound to methionine, enhancing its absorption and retention in the body. This form is readily incorporated into proteins, serving as a selenium reservoir.

The product is manufactured under strict quality control to meet USP/EP standards. It is available in various particle sizes to suit different formulation needs, ensuring optimal flow and blendability.

Key Applications

  • Dietary Supplements: Used in tablets, capsules, and softgels for selenium supplementation, often combined with vitamins and minerals.
  • Clinical Nutrition: Added to enteral and parenteral nutrition formulas to prevent selenium deficiency in patients.
  • Functional Foods: Incorporated into fortified foods and beverages to enhance nutritional value.
  • Pharmaceuticals: Used in prescriptions for selenium deficiency and as an adjunct in antioxidant therapies.
  • Animal Nutrition: Supplemented in animal feed to improve health and productivity.

Quality & Standards

Parameter Specification
Assay (HPLC) ≥98.0%
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Arsenic ≤2 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent
Residue on Ignition ≤0.1%

Packaging & Supply

  • Packaging: 25 kg fiber drum with double polyethylene bags, or as per customer request.
  • MOQ: 1 kg
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.

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