L-Lysine-L-aspartate

L-Lysine-L-aspartate

Product Name L-Lysine-L-aspartate
CAS Number 27348-32-9
Appearance White to off-white crystalline powder
Specifications ≥98.0% (HPLC)
Molecular Formula C10H21N3O6
Molecular Weight 279.29 g/mol
Solubility Soluble in water
Package 25 kg fiber drum with double polyethylene liner

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L-Lysine-L-aspartate Structure

Synonyms: L-Lysine L-Aspartate, Lysine Aspartate, L-Lysine L-Aspartate Salt, (S)-Lysine (S)-Aspartate, Lys-Asp

L-Lysine-L-aspartate is a crystalline salt formed by the combination of two essential amino acids: L-lysine and L-aspartic acid. This compound is widely used in the pharmaceutical and nutraceutical industries as a source of both amino acids in a single, highly bioavailable form. L-lysine is an essential amino acid critical for protein synthesis, calcium absorption, and collagen formation, while L-aspartic acid plays a key role in the urea cycle and neurotransmitter function. The salt form offers improved stability and solubility compared to the individual amino acids, making it a preferred choice for formulations requiring precise dosing and rapid absorption.

Chemically, L-Lysine-L-aspartate is a 1:1 salt where the carboxyl group of L-aspartic acid interacts with the amino group of L-lysine, forming a stable ionic bond. This arrangement enhances the solubility of both amino acids and allows for a synergistic effect when administered together. The compound is often compared to other lysine salts, such as L-lysine hydrochloride, but the aspartate salt provides a more balanced amino acid profile and is particularly valued in sports nutrition and clinical nutrition for its role in energy metabolism and muscle recovery.

Standardized to ≥98.0% purity (HPLC), L-Lysine-L-aspartate is available in white to off-white crystalline powder form. It is primarily used in dietary supplements, sports nutrition products, clinical nutrition formulations, and pharmaceutical preparations. Its high water solubility and neutral taste make it suitable for a wide range of dosage forms, including tablets, capsules, powders, and liquid concentrates. As the demand for amino acid-based therapies grows, L-Lysine-L-aspartate has become a staple ingredient for formulators seeking reliable, dual-action amino acid supplementation.

Function

  • Protein synthesis support: Provides both lysine and aspartate for building blocks in protein metabolism.
  • Energy production: Aspartate participates in the malate-aspartate shuttle and urea cycle, aiding cellular energy.
  • Muscle recovery: Supports muscle tissue repair and reduces fatigue after exercise.
  • Calcium absorption: Lysine enhances intestinal calcium uptake and collagen cross-linking.
  • Neurotransmission: Aspartate acts as an excitatory neurotransmitter and precursor to NMDA.
  • Immune function: Lysine is essential for immune cell proliferation and antibody production.

Source & Standardization

  • Source: Synthetic or fermentation-derived L-lysine and L-aspartic acid
  • Production: Controlled salt formation reaction, followed by crystallization and drying
  • Standardization: ≥98.0% (HPLC)
  • Forms: White to off-white crystalline powder
  • Applications: Dietary supplements, sports nutrition, clinical nutrition, pharmaceuticals

Specifications

Parameter Specification
Assay ≥98.0% (HPLC)
Identification IR, HPLC retention time conforms to standard
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Microbial Limits Total aerobic count ≤1000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli absent

Documentation & Supply

  • Monthly capacity: 5 metric tons
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request
  • Packaging: 25 kg fiber drum with double polyethylene liner; customized packaging available

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