Kopexil

Kopexil

Product Name Kopexil
CAS Number 74638-76-9
Molecular Formula C₉H₁₂N₂OS
Molecular Weight 196.27 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥ 99.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Melting Point 148 – 151°C
Storage Store in a cool, dry place, protected from light
Solubility Soluble in ethanol, DMSO, propylene glycol; slightly soluble in water

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Synonyms: Kopexil, 2-Mercapto-5-(pyrrolidin-1-ylmethyl)pyridine, 2-Mercapto-5-(1-pyrrolidinylmethyl)pyridine, 5-(1-Pyrrolidinylmethyl)-2-pyridinethiol, Hair growth stimulant, Kopeksin, 5-(Pyrrolidin-1-ylmethyl)pyridine-2-thiol,DIAMINOPYRIMIDINE OXIDE

Kopexil is a small-molecule hair growth stimulant that has been studied for its ability to promote hair follicle activity and prolong the anagen (growth) phase of the hair cycle. It belongs to the class of pyridine thiol derivatives and is structurally distinct from other hair growth compounds, such as minoxidil, offering a different mechanism of action.

Kopexil is believed to function as a hair growth stimulant by acting as a potassium channel opener and by modulating cellular signaling pathways in dermal papilla cells, which are critical for hair follicle function. These mechanisms are thought to increase nutrient and oxygen supply to hair follicles, supporting hair growth and reducing hair loss.

Kopexil is widely used in cosmetic and personal care formulations for hair loss treatment, hair growth serums, and scalp care products. It is also used as a research reagent in dermatological studies.

 

Function

  • Hair growth stimulation: Prolongs the anagen phase of the hair cycle.

  • Potassium channel modulation: May open potassium channels in hair follicle cells.

  • Dermal papilla support: Activates signaling pathways in dermal papilla cells.

  • Scalp circulation: Supports nutrient and oxygen delivery to hair follicles.

  • Topical application: Suitable for serums, lotions, and shampoos.


Source & Purity

  • Source: Synthetic chemical synthesis

  • Standardization: ≥99.0% kopexil (HPLC)

  • Forms: White to off-white crystalline powder

  • Applications: Hair growth products, scalp care formulations, cosmetic serums, research studies

Specifications

Parameter Specification
Kopexil Content (HPLC) ≥ 99.0%
Identification IR / MS / NMR conforms to reference
Melting Point 148 – 151°C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm
Arsenic (As) ≤ 1 ppm
Microbial Limits Conforms to USP/EP standards

Documentation & Supply

  • Monthly capacity: 50+ kg

  • Lead time: 3–5 days (samples), 10–15 days (bulk)

  • Documentation: COA, MSDS, TDS

  • Packaging: 1 kg, 5 kg, 10 kg, 25 kg

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