Ipamorelin

Synonyms: NNC 26-0161, Ipamorelin acetate, Aib-His-D-2-Nal-D-Phe-Lys-NH2

Ipamorelin is a synthetic pentapeptide and a selective growth hormone secretagogue (GHS) that acts as a ghrelin receptor agonist. First developed by Novo Nordisk in the 1990s, it was designed to stimulate growth hormone release with minimal effect on other hormones. Unlike older GHS compounds, Ipamorelin does not significantly elevate cortisol, prolactin, or aldosterone, making it a preferred research tool for studying GH secretion pathways.

Chemically, Ipamorelin is a short peptide with the sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2. The incorporation of non-natural amino acids such as Aib (α-aminoisobutyric acid) and D-2-Nal (D-2-naphthylalanine) enhances its stability and receptor selectivity. Its molecular formula is C38H49N9O5, and it has a molecular weight of 711.85 g/mol. The peptide is typically supplied as a lyophilized powder to ensure stability during storage and transport.

In the B2B market, Ipamorelin is primarily used as a reference standard or active ingredient in research settings, including studies on growth hormone regulation, muscle wasting, and metabolic disorders. It is also employed in the development of diagnostic assays and as a comparator in peptide synthesis. Our Ipamorelin is manufactured via solid-phase peptide synthesis and purified by HPLC to achieve ≥98% purity, meeting the stringent requirements of pharmaceutical and research applications.

Function & Mechanism

• Growth hormone release: Binds to the ghrelin receptor (GHS-R1a) in the pituitary, triggering GH secretion without affecting other hormones.
• Selective action: Minimal impact on cortisol, prolactin, and aldosterone levels, making it a clean research tool.
• Stability: Resistant to enzymatic degradation due to D-amino acids and Aib residues, allowing for longer half-life in vivo.
• Anabolic effects: Studied for its potential to increase lean muscle mass and bone density through GH-mediated pathways.
• Diagnostic use: Used in assays to assess pituitary function and GH deficiency.

Source & Standardization

• Source: Synthetic peptide produced by solid-phase peptide synthesis.
• Extraction: Not applicable (synthetic).
• Standardization: ≥98.0% purity by HPLC; identity confirmed by mass spectrometry.
• Forms: Lyophilized powder in sealed vials.
• Applications: Research on GH secretion, pharmaceutical development, diagnostic kits.

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Monthly capacity: 10 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request
• Packaging: Lyophilized powder in sealed vials, secondary packaging in aluminum pouches

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Ipamorelin?

We offer flexible MOQs starting from 1 mg for research purposes. For bulk orders, please contact us for a quote.

What is the delivery time?

For stock items, delivery is within 3-5 business days after order confirmation.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is provided with every shipment. Samples are available upon request for evaluation.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.