Icariin

Icariin

Product Name Icariin
CAS Number 489-32-7
Molecular Formula C33H40O15
Molecular Weight 676.66 g/mol
Appearance Yellow to light brown powder
Specifications 10% - 98% (HPLC)
Solubility Soluble in DMSO, ethanol, and methanol; slightly soluble in water
Assay (HPLC) 10% min, 98% min
Loss on Drying ≤5.0%
Heavy Metals ≤10 ppm
Package 1 kg, 5 kg, 25 kg, or customized
Specification 10% -98%

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Icariin Structure

What is Icariin?

Icariin is a prenylated flavonol glycoside that stands out in the botanical world for its broad-spectrum bioactivity. It’s the primary active compound in Epimedium species, commonly known as Horny Goat Weed, and has been a cornerstone in traditional Chinese medicine for centuries. Today, it’s gaining serious traction in sports nutrition, men’s health, and bone health formulations.

Synonyms: Iearine, Epimedium extract, Horny Goat Weed extract, 2-(4′-methoxyphenyl)-3,4,6-trihydroxy-7-glucosyloxy-8-(3-methylbut-2-enyl)-4H-chromen-4-one

Icariin Sources

Icariin is naturally found in the aerial parts of Epimedium plants, including Epimedium brevicornu, Epimedium sagittatum, and Epimedium koreanum. The concentration varies by species and harvest time, so reliable extraction and standardization are crucial. We source our raw material from cultivated farms in China, ensuring consistent quality and traceability.

Icariin Bioavailability

One of the challenges with icariin is its low oral bioavailability due to poor water solubility and rapid metabolism. But don’t let that scare you off. Many formulators pair icariin with piperine or use advanced delivery systems like cyclodextrin complexation to enhance absorption. When you source from us, we provide technical guidance on formulation to help you get the most out of this compound.

Icariin Manufacturing Process

Our icariin is produced through a meticulous process: dried Epimedium leaves are extracted with ethanol, concentrated, and then purified using column chromatography to achieve the desired purity. For 98% purity, we employ repeated crystallization. Every batch is rigorously tested via HPLC to confirm purity and contaminants, and each shipment includes a Certificate of Analysis (COA).

Icariin Specifications & Applications

We offer icariin in a range of purities from 10% to 98% to suit different applications. Lower purities (10%-20%) are ideal for dietary supplements and herbal extracts, while higher purities (90%-98%) are preferred for research and pharmaceutical use. Icariin is commonly used in products targeting erectile dysfunction, osteoporosis, and athletic performance enhancement. Its ability to modulate PDE5 and increase nitric oxide production makes it a popular natural alternative in men’s health supplements.

Where to Buy Icariin Powder in Bulk?

Looking for a reliable supply of icariin? We keep multiple purity grades in stock year-round, with flexible packaging (1 kg / 5 kg / 25 kg) and fast worldwide delivery. Whether you need a few kilograms for R&D or metric tons for commercial production, we’ve got you covered. Bulk quantities welcome — contact us for a quote and samples.

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  • Our Address: 280 Main Street, Xian, Shaanxi, China
  • LyvBio Co., Ltd. — Email: info@lyvbio.com

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