Hydroxocobalamin Hydrochloride

Synonyms: Hydroxocobalamin hydrochloride, Vitamin B12a hydrochloride, Hydroxycobalamin hydrochloride, Cobalamin, hydroxo-, monohydrochloride, Aquacobalamin hydrochloride

Hydroxocobalamin hydrochloride is the hydrochloride salt form of hydroxocobalamin, a natural cobalamin (vitamin B12) analog in which the cobalt center carries a hydroxyl ligand. It appears as a dark red crystalline powder, freely soluble in water, and is produced via microbial fermentation followed by chemical modification and purification. Our material is supplied as a high-purity, pharmaceutical-grade ingredient suitable for injectable and other regulated applications.

As a stable and versatile form of vitamin B12, hydroxocobalamin hydrochloride is widely utilized in pharmaceutical formulations, including cyanide antidotes and vitamin B12 replacement therapies. Its excellent solubility and rapid conversion to active coenzyme forms make it a preferred choice for parenteral nutrition and research settings. The compound is also employed as a reference standard and in diagnostic kits.

Product Highlights

• High Purity: ≥98% assay by HPLC, ensuring consistent potency and low impurity profiles.
• Regulatory Compliance: Manufactured in cGMP facilities, supported by DMF and CEP where applicable.
• Fermentation-Based: Produced through sustainable microbial fermentation, free from animal-derived components.
• Stability: Superior stability in aqueous solutions compared to cyanocobalamin, with a long shelf life.
• Global Supply: Reliable supply chain with stock available in multiple warehouses.
• Technical Support: Dedicated team to assist with formulation and regulatory inquiries.

Applications

• Pharmaceutical injectables for cyanide poisoning and vitamin B12 deficiency.
• Parenteral nutrition solutions and multivitamin infusions.
• Research on cobalamin metabolism and enzyme cofactor functions.
• Analytical reference standards for HPLC and LC-MS.
• Diagnostic reagents and biochemical assays.

Specifications

Ordering & Supply

• Packaging: 25 kg fiber drum with double polyethylene liners, or customized packaging upon request.
• MOQ: 1 kg for standard orders; flexible for bulk quantities.
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, DMF, CEP, and other regulatory support provided.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com