Hexapeptide-9

Synonyms: Hexapeptide-9, H-9, Palmitoyl Hexapeptide-9, CAS 1228371-11-6, N-Acetyl Hexapeptide-9, Hexapeptide-9 Acetate

Hexapeptide-9 is a synthetic peptide built from six amino acids, designed to support skin repair and firmness. Unlike many peptides that primarily target expression lines, Hexapeptide-9 works on the structural integrity of the dermal matrix, making it a valuable active for mature skin and post-procedure care. It has become a staple in high-performance anti-aging formulations, often combined with other peptides and retinoids for synergistic effects.

Structurally, Hexapeptide-9 is a short chain that mimics a fragment of human collagen, allowing it to interact with fibroblasts and stimulate the production of key extracellular matrix components. Its small size enables efficient penetration through the stratum corneum, where it can exert its biological activity. The peptide is typically supplied as a lyophilized powder or in solution, and is compatible with a wide range of cosmetic ingredients.

In the personal care industry, Hexapeptide-9 is standardized to high purity, usually ≥95% as determined by HPLC. It is incorporated into serums, creams, and masks aimed at reducing the appearance of wrinkles, improving elasticity, and enhancing skin density. Its efficacy and safety profile make it suitable for daily use and for products targeting sensitive or compromised skin.

Function

• Collagen stimulation: Promotes synthesis of type I and III collagen in fibroblasts.
• Skin firming: Improves elasticity and reduces sagging by reinforcing the dermal matrix.
• Wrinkle reduction: Smooths fine lines and deep wrinkles, particularly around the eyes and mouth.
• Wound healing support: Accelerates tissue repair and regeneration.
• Barrier enhancement: Strengthens the skin barrier function and improves moisture retention.

Source & Standardization

• Source: Synthetic peptide produced by solid-phase peptide synthesis.
• Purity: ≥95% (HPLC).
• Form: White to off-white powder.
• Standardization: Each batch is tested for assay, identification, and impurities.
• Applications: Anti-aging serums, creams, eye care, and post-procedure products.

Specifications

Documentation & Supply

• Monthly capacity: 10 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS available upon request.
• Packaging: 1 g, 10 g, 100 g, 1 kg in amber glass vials or aluminum foil bags.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com