Hexapeptide-12

Hexapeptide-12

Product Name Hexapeptide-12
CAS Number 92899-39-3
Molecular Formula C34H62N12O8
Molecular Weight 790.9 g/mol
Appearance White to off-white powder
Assay (HPLC) ≥98.0%
Solubility Soluble in water
Package 1 g, 5 g, 10 g, 50 g, 100 g

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Synonyms: Hexapeptide-12, Vialox, Pentapeptide-3, CAS 92899-39-3, Hexapeptide-12 Acetate, L-Arginine Hexapeptide-12

Hexapeptide-12 is a synthetic peptide composed of six amino acids, with the sequence Arg-Arg-Arg-Arg-Arg-Arg. It is a highly cationic molecule, supplied as a white to off-white powder, and is available in cosmetic and pharmaceutical grades. Our Hexapeptide-12 is produced by solid-phase peptide synthesis and purified by HPLC to a minimum purity of 98%.

In the personal care industry, Hexapeptide-12 is recognized as a safe and effective alternative to botulinum toxin for topical applications. It functions by inhibiting neurotransmitter release at the neuromuscular junction, thereby reducing the depth of expression lines and wrinkles. Formulators incorporate it into anti-aging serums, creams, and gels, often in combination with other peptides for synergistic effects. Beyond cosmetics, it is also explored in pharmaceutical research for its potential in muscle relaxation and pain management.

Function

  • Anti-wrinkle activity: Reduces the intensity of facial wrinkles by interfering with SNARE complex formation.
  • Muscle relaxation: Inhibits acetylcholine release at the neuromuscular junction, leading to a smoothing effect on the skin.
  • Collagen stimulation: May promote collagen synthesis and improve skin elasticity.
  • Neurotransmitter modulation: Acts as a competitive inhibitor of synaptosomal-associated protein 25 (SNAP-25).

Source & Standardization

  • Source: Synthetic peptide produced by solid-phase peptide synthesis.
  • Purity: ≥98.0% (HPLC).
  • Form: White to off-white powder.
  • Solubility: Soluble in water and aqueous buffers.
  • Standardization: Each batch is tested for appearance, assay, water content, and heavy metals.

Specifications

Parameter Specification
Appearance White to off-white powder
Assay (HPLC) ≥98.0%
Water Content ≤5.0%
Heavy Metals ≤10 ppm
Solubility Soluble in water
Storage Store at -20°C, protected from light and moisture

Documentation & Supply

  • Packaging: 1 g, 5 g, 10 g, 50 g, 100 g in amber glass vials or as requested.
  • MOQ: 1 g
  • Lead time: 3-5 business days for small quantities; 2-3 weeks for bulk orders.
  • Documentation: COA, MSDS, TDS available upon request.
  • Storage: Store at -20°C, protected from light and moisture.

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