Folic acid

Synonyms: Vitamin B9, Pteroylglutamic Acid, Folacin, PGA, N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid

Folic acid is a synthetic, water-soluble form of vitamin B9 that serves as the parent compound of the folate family. It is produced commercially through a multi-step chemical synthesis starting from 2,4,5-triamino-6-hydroxypyrimidine, yielding a stable, crystalline powder that is standardized to pharmacopoeial grades such as USP, EP, and BP. Unlike natural food folates, this synthetic form is oxidatively stable, highly pure, and readily available for accurate dosing in pharmaceutical and nutritional applications.

Folic acid is one of the most widely used micronutrients in the pharmaceutical and nutraceutical industries, primarily due to its well-established role in preventing neural tube defects and supporting red blood cell formation. It is a key ingredient in prenatal supplements, multivitamin formulations, and fortified foods, and it also serves as a critical raw material for the production of methotrexate and other antifolate drugs. Its compatibility with common excipients and excellent stability profile make it a preferred choice for solid dosage forms and liquid concentrates alike.

Product Highlights

• High purity and consistent quality: Assay 97.0%–102.0% on dried basis, meeting USP/EP/BP requirements for pharmaceutical use.
• Regulatory compliance: Manufactured in a GMP-certified facility with full documentation including COA, MSDS, and TDS.
• Reliable supply chain: Annual production capacity of 500 metric tons, ensuring stable supply for large-scale pharmaceutical and nutraceutical manufacturers.
• Versatile handling: Available in powder form with controlled particle size, suitable for direct compression, wet granulation, and liquid filling.
• Global logistics support: Prompt shipment from multiple warehouses, with cold-chain options available upon request.
• Customized packaging: Standard 25 kg fiber drums or smaller aliquots for pilot and clinical trial batches.

Applications

• Pharmaceutical formulations: Used in prenatal vitamins, anemia treatments, and as an adjunct in methotrexate therapy.
• Dietary supplements: A key component of multivitamin tablets, capsules, and gummies, often combined with other B-complex vitamins.
• Food fortification: Added to flour, cereals, and infant formula to prevent folate deficiency in populations.
• Clinical nutrition: Incorporated into enteral and parenteral nutrition solutions for hospitalized patients.
• Research and diagnostics: Employed as a reference standard and in microbiological assays for folate determination.

Specifications

Ordering & Supply

• Packaging: 25 kg fiber drums with double polyethylene inner liners; custom packaging available for small quantities.
• MOQ: 1 kg for pilot orders; 25 kg for commercial orders.
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, and additional regulatory support (e.g., DMF) provided upon request.
• Storage: Store in a cool, dry place, protected from light and moisture.

Request For Quote

• LyvBio Co., Ltd. — Email: info@lyvbio.com