Fenbendazole

Fenbendazole

Parameter Specification
Product Name Fenbendazole
CAS Number 43210-67-9
Molecular Formula C15H13N3O2S
Molecular Weight 299.35 g/mol
Appearance White to off-white crystalline powder
Assay (HPLC) ≥99.0%
Solubility Slightly soluble in water, soluble in dimethyl sulfoxide and dimethylformamide
Package 25 kg fiber drum with double polyethylene liner

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Fenbendazole Structure

Synonyms: Fenbendazole, Methyl 5-(phenylthio)-1H-benzimidazol-2-ylcarbamate, HOE 881, Panacur, Safe-Guard, 43210-67-9

Fenbendazole is a broad-spectrum anthelmintic belonging to the benzimidazole class. Since its introduction in the 1970s, it has become a staple in veterinary medicine for controlling gastrointestinal nematodes, cestodes, and certain protozoa in livestock, companion animals, and exotic species.

Its chemical structure, featuring a phenylthio group at the 5-position of the benzimidazole ring, enhances its anthelmintic potency and spectrum compared to earlier benzimidazoles like thiabendazole. This modification also contributes to its favorable safety profile in target animals.

LyvBio supplies fenbendazole with a purity of ≥99.0% (HPLC), ensuring consistent efficacy and compliance with pharmacopeial standards. Our product is manufactured under cGMP conditions and is available for immediate shipment.

Function & Mechanism

  • Microtubule disruption: Binds to β-tubulin, inhibiting microtubule polymerization and impairing parasite cellular functions.
  • Energy metabolism inhibition: Reduces glucose uptake and ATP production in helminths.
  • Broad-spectrum activity: Effective against a wide range of nematodes, cestodes, and some trematodes.
  • Ovicidal effect: Prevents egg development and larval hatching in treated animals.

Source & Standardization

  • Source: Synthetic benzimidazole derivative
  • Manufacturing: Chemical synthesis under cGMP conditions
  • Standardization: ≥99.0% fenbendazole (HPLC)
  • Forms: White to off-white crystalline powder
  • Applications: Veterinary dewormers, pharmaceutical formulations, research

Quality Specifications (QC Tests)

Test Item Specification
Identification IR spectrum matches reference standard
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤20 ppm
Organic Impurities ≤0.5% total, ≤0.1% individual
Residual Solvents Meets ICH Q3C requirements

Bulk Supply & Documentation

  • Monthly capacity: 5 metric tons
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request
  • Packaging: 25 kg fiber drum with double polyethylene liner

Frequently Asked Questions

What is the minimum order quantity (MOQ)?

Our MOQ is 1 kg for standard packaging, but we can accommodate smaller quantities for research purposes. Please contact us for details.

What is the delivery time?

For stock items, delivery is 3-5 business days after order confirmation. We ship globally via air or sea freight.

Do you provide COA and samples?

Yes, we provide a COA for each batch and can send samples for evaluation. Sample delivery typically takes 1-2 days.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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