Donepezil HCl

Donepezil HCl

Product Name Donepezil HCl
CAS Number 120011-70-3
Molecular Formula C24H29NO3·HCl
Molecular Weight 415.95
Appearance White to off-white crystalline powder
Assay (HPLC) ≥99%
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Melting Point 223-227°C
Specific Rotation Not applicable (racemic mixture)
Specification 99%

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Donepezil HCl Structure

Synonyms

Donepezil hydrochloride, Aricept, E2020, Donepezil HCl, 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride

Donepezil HCl is a well-established acetylcholinesterase inhibitor, widely recognized for its role in managing Alzheimer’s disease. As a high-purity pharmaceutical intermediate, it is essential for formulations targeting cognitive disorders. Our supply ensures consistent quality, backed by rigorous testing and reliable sourcing.

We offer Donepezil HCl in bulk quantities, ideal for both research and commercial production. With a purity of ≥99%, it meets the stringent requirements of pharmaceutical manufacturers. Our team is committed to providing competitive pricing and timely delivery, making us a trusted partner for your supply chain needs.

Function

  • Mechanism of Action: Inhibits acetylcholinesterase, increasing acetylcholine levels in the brain, which is crucial for cognitive function.
  • Therapeutic Use: Primarily used in the symptomatic treatment of mild to moderate Alzheimer’s disease, improving memory and daily function.
  • Research Applications: Valuable in neuroscience research for studying cholinergic pathways and developing novel treatments for dementia.

Source & Purity

  • Source: Synthesized via a multi-step chemical process, ensuring high enantiomeric purity and batch-to-batch consistency.
  • Standardization: Each batch is tested for purity (≥99% by HPLC), loss on drying, residue on ignition, and heavy metals, with COA provided.
  • Forms: Available as a white crystalline powder, packaged in sealed containers to maintain stability.
  • Applications: Suitable for pharmaceutical formulations, including tablets and oral solutions, as well as for research purposes.

Documentation & Supply

  • Documentation: COA, MSDS
  • Lead time: In stock for immediate dispatch; bulk orders typically shipped within 7-10 days.
  • Packaging: Available in 1kg, 5kg, 25kg drums, or custom packaging upon request.

Request For Quote

  • Our Address: 280 Main Street, Xian, Shaanxi, China
  • LyvBio Co., Ltd. — Email: info@lyvbio.com

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