Domperidone

Synonyms

Domperidone base, R33812, NSC 299589, (±)-5-Chloro-1-(1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

Domperidone is the go-to dopamine antagonist for gastrointestinal motility disorders, and it’s earned that spot by doing something most prokinetics don’t: it works peripherally without crossing the blood-brain barrier in significant amounts. That means it relieves nausea and vomiting while keeping neurological side effects minimal — a major plus for chronic use.

For formulators, that translates into a reliable API for antiemetic and gastroprokinetic products. We supply domperidone as a high-purity crystalline powder, every batch shipped with a full COA, flexible from 1 kg trial runs to bulk container orders, and ready for worldwide delivery.

Function

• Antiemetic: Blocks dopamine D2 receptors in the chemoreceptor trigger zone to control nausea and vomiting.
• Gastroprokinetic: Enhances gastric emptying and upper GI motility, making it effective for dyspepsia and gastroparesis.

Source & Purity

• Purity: ≥99.0% by HPLC, meeting EP/USP standards.
• Appearance: White or almost white crystalline powder, free of visible impurities.

Documentation & Supply

• Documentation: COA, MSDS, TDS
• Lead time: In stock for quick dispatch; lead time 3-5 days for standard orders.
• Packaging: 1 kg foil bags, 25 kg fiber drums, or customized to your requirement.

Request For Quote

• Our Address: 280 Main Street, Xian, Shaanxi, China
• LyvBio Co., Ltd. — Email: info@lyvbio.com