Dihydromyricetin

Dihydromyricetin

Parameter Specification
Product Name Dihydromyricetin
CAS Number 27200-12-0
Molecular Formula C15H12O8
Molecular Weight 320.25 g/mol
Appearance Off-white to light yellow crystalline powder
Assay (HPLC) ≥98.0%
Solubility Sparingly soluble in water, soluble in ethanol and DMSO
Package 25 kg fiber drum with double PE liner

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Dihydromyricetin Structure

Synonyms: Ampelopsin, DHM, 3,5,7,3′,4′,5′-Hexahydroxyflavanone, (2R,3R)-Dihydromyricetin, Ampelopsis grossedentata extract

Dihydromyricetin (DHM) has moved from a niche flavonoid to a mainstream ingredient in the supplement and functional beverage space, largely on the back of its well-publicized support for alcohol metabolism and liver health. Formulators like it because it is a single, well-characterized molecule with a clean analytical profile, not a complex botanical blend. In the past few years, demand has grown steadily across the US, Europe, and Asia, with buyers looking for reliable high-purity material at commercial scale.

Chemically, DHM is a flavanonol—a dihydroflavonol—found most abundantly in the young leaves and stems of Ampelopsis grossedentata, a vine known locally as vine tea or rattan tea. The plant has a long history in southern China, where the leaves are brewed as a daily beverage. Commercial DHM is typically obtained by hot-water extraction of the dried leaves, followed by purification steps that yield a crystalline powder with a characteristic off-white to pale yellow color.

Standard grades are offered at ≥98% purity by HPLC, which is the benchmark most quality-conscious buyers now expect. At this level, DHM is suitable for capsules, tablets, stick packs, and ready-to-drink formats. It also serves as a reference standard and research material for laboratories studying its antioxidant, anti-inflammatory, and metabolic effects.

Product Overview & Composition

Dihydromyricetin is a single chemical entity, not a mixture of related flavonoids. Its structure carries six hydroxyl groups, which accounts for its strong radical-scavenging behavior and its limited solubility in cold water. In the solid state it is a crystalline powder that is stable under normal storage conditions, though it should be protected from prolonged exposure to light and moisture.

Because DHM is a pure compound, buyers can rely on a consistent assay and a simple impurity profile. The main quality markers are residual solvents from extraction, heavy metals, and microbial limits—all routinely tested on every batch. There is no need to worry about variable ratios of co-occurring flavonoids, which is a common headache with botanical extracts.

Applications & Product Lines

  • Liver support and hangover formulas: DHM is a popular choice for products aimed at alcohol metabolism, often combined with electrolytes, B vitamins, or milk thistle.
  • Antioxidant and wellness capsules: Used as a standalone ingredient or in blends targeting oxidative stress and general vitality.
  • Sports nutrition and hydration: Added to pre-workout and recovery drinks, where its solubility in warm water is adequate for most formulations.
  • Functional foods and beverages: Suitable for dry mixes, gummies, and ready-to-drink formats, though taste masking may be needed due to its slightly astringent note.
  • Cosmetic and personal care: Incorporated into skincare products for its antioxidant properties, often in emulsions or serums.
  • Research and reference standards: Supplied to analytical labs and academic groups as a high-purity reference material.

Quality Control Standards

Test Item Specification
Identification IR and HPLC retention time match reference standard
Loss on Drying ≤ 2.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 10 ppm
Organic Impurities ≤ 1.0% total
Microbial Limits Total aerobic count ≤ 1000 CFU/g; yeast and mold ≤ 100 CFU/g; E. coli and Salmonella absent

Bulk Packaging & Supply

  • Packaging: 25 kg fiber drum with double PE liner; smaller pack sizes available on request.
  • MOQ: 1 kg for trial orders; 25 kg for standard commercial orders.
  • Lead time: 3-5 business days from order confirmation for stock items.
  • Documentation: COA, MSDS, TDS, and nutritional data sheets provided with each shipment.

Frequently Asked Questions

What is your minimum order quantity?

We can supply from 1 kg for trial and development work, with 25 kg being the standard commercial pack size. Larger volumes are available and can be quoted on request.

How long does delivery take?

For stock items, we ship within 3-5 business days from order confirmation. We keep regular inventory of DHM, so most orders go out without delay.

Can you provide a COA and sample before I place a bulk order?

Yes. A current COA and MSDS are available for every batch, and we can send a small sample for your own testing. Sample dispatch usually takes 1-2 days.

Contact & Ordering Information

  • Company: LyvBio Co., Ltd.
  • Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
  • Email: info@lyvbio.com
  • Phone: +86-29-65816888

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Room,5-0203, Unit 5, Beiyuanmen Street,Xi'an,Shaanxi,China

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