Cooling Agent WS-27

Cooling Agent WS-27

Product Name Cooling Agent WS-27
Other Names N,2,3-Trimethyl-2-(propan-2-yl)butanamide; WS-27; Cooling Agent 27
CAS Number 51115-70-9
Molecular Formula C10H21NO
Molecular Weight 171.28 g/mol
Appearance White crystalline powder
Assay (GC) ≥99.0%
Melting Point 58–62 °C
Solubility Soluble in ethanol, propylene glycol, and most non-polar solvents; practically insoluble in water
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Package 25 kg net fiber drum with double polyethylene liner

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Cooling Agent WS-27 Structure

Synonyms: N,2,3-Trimethyl-2-(propan-2-yl)butanamide, WS-27, Cooling Agent 27, N,2,3-Trimethyl-2-isopropylbutanamide, 2-Isopropyl-N,2,3-trimethylbutyramide

Cooling Agent WS-27 is a synthetic alkylamide cooling compound that belongs to the same structural family as the well-known WS-23. It features a trimethyl-substituted butanamide backbone with an isopropyl group, delivering a clean, intense cooling sensation without the minty or bitter notes associated with menthol.

Because it is odorless and non-volatile, WS-27 integrates smoothly into formulations where a neutral sensory profile is essential. It is widely used in oral care, confectionery, beverages, and topical products, as well as in pharmaceutical and nutraceutical applications requiring a controlled cooling effect.

Our WS-27 is manufactured under strict quality control and is available in commercial quantities with full documentation. It meets the requirements of major regulatory frameworks and is suitable for use in products marketed globally.

Product Highlights

  • High purity: ≥99.0% assay (GC), ensuring consistent performance and minimal off-notes.
  • Potent cooling: Effective at low concentrations, typically 0.01–0.05% in oral care and 0.005–0.02% in beverages.
  • Odorless and non-volatile: Does not interfere with flavor profiles, ideal for delicate formulations.
  • Regulatory support: Compliant with FCC, USP/NF, and EU food contact standards; documentation available upon request.
  • Reliable supply: Commercial-scale production with a monthly capacity of 5 metric tons, ensuring timely delivery.
  • Custom packaging: Available in 1 kg, 5 kg, and 25 kg drums to suit pilot to production needs.

Applications

  • Oral care products: toothpastes, mouthwashes, and chewing gums for long-lasting freshness.
  • Confectionery and beverages: candies, soft drinks, and energy drinks for a cooling sensation without mint.
  • Topical formulations: creams, gels, and patches for a soothing effect.
  • Pharmaceuticals: throat lozenges, cough syrups, and topical analgesics.
  • Nutraceuticals: pre-workout supplements and weight management products.

Specifications

Parameter Specification
Assay (GC) ≥99.0%
Appearance White crystalline powder
Melting Point 58–62 °C
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Solubility Soluble in ethanol, propylene glycol; insoluble in water

Ordering & Supply

  • Packaging: 25 kg fiber drum with double polyethylene liner; custom packaging available.
  • MOQ: 1 kg for sample orders; 25 kg for bulk orders.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and regulatory statements provided with each shipment.

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