Choline hydroxide

Choline hydroxide

Product Name Choline hydroxide
CAS Number 123-41-1
Molecular Formula C5H15NO2
Molecular Weight 121.18 g/mol
Appearance Colorless to slightly yellow viscous liquid
Assay 45% in water or methanol
Density 1.09 g/cm³ at 20 °C
pH Strongly alkaline (pH >13)
Solubility Miscible with water, alcohols
Package 200 kg drums, 1000 kg IBCs

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Choline hydroxide Structure

Synonyms: (2-Hydroxyethyl)trimethylammonium hydroxide, Choline hydroxide solution, 2-Hydroxy-N,N,N-trimethylethanaminium hydroxide, Choline base

Choline hydroxide is a quaternary ammonium hydroxide with the chemical formula C5H15NO2, typically supplied as a 45% aqueous or methanolic solution. It is a strong organic base, colorless to slightly yellow, with a characteristic amine-like odor. The compound is manufactured through the reaction of choline chloride with potassium hydroxide or via ion exchange, followed by concentration to the desired strength.

In the pharmaceutical and chemical industries, choline hydroxide serves as a versatile intermediate and reagent. It is used in the synthesis of choline salts, such as choline bitartrate and choline citrate, and as a phase-transfer catalyst in organic reactions. Its high alkalinity and solubility make it valuable in various applications, from electronics to agrochemicals.

Product Highlights

  • High purity: Available at 45% concentration with low impurity levels, suitable for pharmaceutical and electronic applications.
  • Versatile reactivity: Acts as a strong base and nucleophile, facilitating a wide range of chemical transformations.
  • Consistent quality: Produced under strict quality control, with batch-to-batch reproducibility.
  • Custom packaging: Offered in various container sizes to meet different scale requirements.
  • Regulatory support: Compliant with REACH and other global regulations; documentation available upon request.
  • Reliable supply: Robust production capacity ensures timely delivery worldwide.

Applications

  • Pharmaceutical intermediates: Used in the synthesis of choline-based drugs and supplements.
  • Phase-transfer catalysis: Enhances reaction rates in biphasic systems.
  • Electronics: Component in photoresist developers and cleaning agents.
  • Agrochemicals: Intermediate for the production of pesticides and herbicides.
  • Ion exchange resins: Precursor for the preparation of anion exchange resins.

Specifications

Parameter Specification
Assay (titration) 45.0% ± 1.0%
Color (APHA) ≤ 50
Water content ≤ 55% (for aqueous solution)
Choline chloride ≤ 0.1%
Heavy metals ≤ 10 ppm
Residue on ignition ≤ 0.1%

Ordering & Supply

  • Packaging: 200 kg polyethylene drums, 1000 kg IBC totes, or custom packaging.
  • MOQ: 1,000 kg.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS available upon request.

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