Cagrilintide

Cagrilintide

Product Name Cagrilintide
CAS Number 1415456-99-3
Synonyms Cagrilintide acetate, Amylin analog, Long-acting amylin analog, NN-9935
Molecular Formula C171H267N43O51
Molecular Weight 3792.3 g/mol
Appearance White to off-white powder
Purity ≥98% (HPLC)
Package 5g, 10g, 50g, custom

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Cagrilintide Structure

Synonyms: Cagrilintide, 1415456-99-3, Amylin analog, Long-acting amylin analog, NN-9935, Cagrilintide acetate

Cagrilintide is a synthetic analog of human amylin, a peptide hormone that works alongside insulin to regulate postprandial glucose levels and signal satiety. Developed by Novo Nordisk, this long-acting amylin analog is designed for once-weekly dosing, making it a promising candidate for obesity and type 2 diabetes management. Its extended half-life is achieved through fatty acid acylation, which promotes albumin binding and slows renal clearance.

Function

  • Amylin receptor agonist: Activates amylin receptors, reducing food intake and delaying gastric emptying.
  • Appetite regulation: Enhances satiety signaling, leading to reduced caloric intake.
  • Weight management: Promotes weight loss in overweight and obese individuals.
  • Glycemic control: Helps regulate postprandial glucose levels.

Source & Standardization

  • Source: Synthetic peptide, produced via solid-phase peptide synthesis.
  • Standardization: Purity ≥98% (HPLC), peptide content 70-90%.
  • Forms: Lyophilized powder, acetate salt.
  • Applications: Research on obesity, type 2 diabetes, and metabolic disorders.

Documentation & Supply

  • MOQ: 5g
  • Monthly capacity: 1 kg
  • Lead time: 5-10 days after order
  • Documentation: COA, MSDS, TDS
  • Packaging: Sealed vials or custom packaging

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