| Product Name | Ketone Ester |
|---|---|
| CAS Number | 1208313-97-6 |
| Molecular Formula | C₈H₁₆O₄ (varies by specific ester) |
| Molecular Weight | ~176.21 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Assay (HPLC) | ≥ 99.0% |
| Flash Point | 101°C |
| Storage Condition | Store at -20°C |
| Solubility | Soluble in methyl acetate: 50 mg/ml |
| Acid Dissociation Constant (pKa) | 14.38 ± 0.20 (Predicted) |
| Heavy Metals | ≤ 10 ppm |
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Synonyms: Ketone Ester, 1,3-Butanediol R-3-Hydroxybutyrate, Monoester of R-3-Hydroxybutyric Acid, KE, Ketone Monoester, R-3-Hydroxybutyl R-3-Hydroxybutyrate
Ketone Ester (KE) is a synthetic exogenous ketone compound designed to rapidly elevate blood β-hydroxybutyrate (BHB) levels without the need for dietary restriction or fasting.
It is chemically a monoester of R-3-hydroxybutyric acid and 1,3-butanediol, which upon ingestion is hydrolyzed in the gastrointestinal tract to release free BHB, providing an immediate and bioavailable source of ketone bodies.
As a metabolic fuel, ketone esters offer an alternative energy substrate to glucose, particularly for brain, cardiac, and skeletal muscle tissues. They are of increasing interest in sports nutrition, cognitive performance, metabolic therapy, and neurological health research.

Ketone Ester (R-BHB)
Rapid ketosis induction: Elevates blood BHB levels within 30–60 minutes post-ingestion.
Alternative fuel source: Provides ketone bodies for brain and muscle energy metabolism.
Cognitive support: May enhance mental clarity, focus, and neuroprotection.
Athletic performance: Supports endurance, reduces reliance on glycogen, and spares muscle glycogen.
Metabolic flexibility: Supports ketogenic diets and metabolic therapies.
Source: Synthetic chemical synthesis
Standardization: ≥99.0% purity (HPLC)
Forms: Colorless to pale yellow liquid
Applications: Sports nutrition, dietary supplements, clinical research, neurological health
| Parameter | Specification |
|---|---|
| Purity (HPLC) | ≥ 99.0% |
| Appearance | Colorless to pale yellow liquid |
| Flash Point | 101°C |
| Solubility | Methyl acetate: 50 mg/ml |
| pKa | 14.38 ± 0.20 (Predicted) |
| Storage | -20°C |
| Heavy Metals | ≤ 10 ppm |
| Residual Solvents | Meets USP requirements |
Monthly capacity: 50+ L
Lead time: 3–5 days (samples), 10–15 days (bulk)
Documentation: COA,HPLC chromatogram, stability data (upon request)
Packaging: 100 mL, 500 mL, 1 L, 5 L, 10 L
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