Azadirachtin B

Synonyms: Azadirachtin B, 3-Deacetylazadirachtin, Azadirachtin B1, Neem extract, Azadirachta indica extract, Nimbolin B, Azadirachtin B (mixture of A and B)

Azadirachtin B is a naturally occurring limonoid isolated from the seeds of the neem tree (Azadirachta indica), a plant deeply rooted in traditional agriculture and medicine across the Indian subcontinent. As a close structural analog of azadirachtin A, it shares the same tetranortriterpenoid backbone but differs in the substitution pattern of the furan ring and the degree of acetylation. This subtle variation influences its biological potency and stability, making it a compound of distinct interest for both agrochemical and pharmaceutical research.

In the neem kernel, azadirachtin B typically constitutes 10–20% of the total azadirachtin content, alongside azadirachtin A and other minor limonoids. Its molecular framework includes a highly oxygenated decalin core, an enol ether bridge, and a tigloyl ester moiety—features that underpin its insect antifeedant and growth-regulating properties. Unlike synthetic pyrethroids, azadirachtin B exhibits low mammalian toxicity and rapid environmental degradation, aligning well with integrated pest management (IPM) programs and organic farming standards.

While azadirachtin A dominates commercial neem formulations, azadirachtin B is increasingly sought as a reference standard and active ingredient in high-purity botanical insecticides. It also serves as a starting material for semi-synthetic derivatives targeting insect hormone pathways. For B2B buyers, the compound is available in research-grade purity (≥95% HPLC) and is supplied with full analytical documentation to support product registration and quality control.

Function & Mechanism

• Insect growth regulation: Disrupts ecdysone and juvenile hormone signaling, causing molting failure and mortality in larvae.
• Antifeedant activity: Deters feeding by binding to chemoreceptors on insect mouthparts, reducing crop damage.
• Oviposition inhibition: Alters female insect behavior, lowering egg-laying on treated surfaces.
• Low mammalian toxicity: Rapidly metabolized in mammals, with no bioaccumulation in the food chain.
• Environmental compatibility: Degrades within days under sunlight and soil microbes, leaving minimal residue.

Source & Standardization

• Source: Seeds of Azadirachta indica (neem tree)
• Extraction: Solvent extraction (e.g., methanol or ethanol) followed by chromatographic purification
• Standardization: ≥95% azadirachtin B by HPLC
• Forms: White to off-white crystalline powder
• Applications: Botanical insecticides, IPM formulations, reference standards, semi-synthetic derivatives

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Monthly capacity: 500 kg
• Lead time: 3-5 business days (stock items)
• Documentation: COA, MSDS, TDS, and additional analytical data upon request
• Packaging: 1 kg, 5 kg, 10 kg in aluminum foil bags or fiber drums

Frequently Asked Questions

What is the minimum order quantity (MOQ) for Azadirachtin B?

Our standard MOQ is 1 kg, but we can accommodate smaller quantities for research and development purposes. Please contact us for custom requirements.

How long does delivery take?

For stock items, we ship within 3-5 business days after order confirmation. We use reliable couriers to ensure timely delivery worldwide.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is provided with every shipment. Samples are available upon request; please specify your requirements and we will arrange shipment within 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.