What is Alpha GPC?

Alpha-GPC is a member of the phospholipid family, as one of the phosphatidylcholine derivatives, playing an important role in the health of cell membranes.

The mainly physiological function of Alpha-GPC is to cross the blood-brain barrier and provide the necessary choline for the biosynthesis of acetylcholine and phosphatidylcholine.

Why do we choose Alpha-GPC, not Beta-GPC?

Beta-glycerylphosphocholine(Beta-GPC) is also a member of phosphocholines.

Beta-GPC contributes very little to total GPC(~1%), while Alpha-GPC is hydrolyzed to phosphorylcholine and contributes to the supply of choline needed by the liver and choline needed for myelin synthesis.

How Does Alpha GPC Work?

When the human body absorbs Alpha-GPC, it is decomposed into choline and glycerophosphate under the action of enzymes in the body. Among them, choline participates in the biosynthesis of acetylcholine, which is a kind of neurotransmitter; glycerophosphate is lecithin Derivatives, involved in the synthesis of lecithin.

The main pharmacological effects of Alpha-GPC include protecting the metabolism of choline; ensuring the synthesis of acetylcholine and lecithin in the nerve membrane.

Alpha-GPC VS CDP Choline(Citicoline) VS Phosphatidylserine

From the source, Alpha-GPC can be obtained naturally from soybean lecithin, or it can be made by synthetic route; CDP Choline is mainly synthetic route; phosphatidylserine (PS) can be obtained from soybean lecithin, sunflower lecithin, etc.

In terms of efficacy, CDP Choline is mainly used as a brain metabolism and neuroactivator, which can promote brain cell respiration, improve brain function, enhance the function of the activation system of the ascending reticular structure, promote recovery, and reduce cerebrovascular resistance; Phosphatidylserine also It is called compound nervonic acid, which is an active substance of cell membrane. Its effect is to improve the function of nerve cells, regulate the conduction of nerve impulses, and enhance the memory function of the brain. Because of its strong lipophilicity, it can quickly enter the brain through the blood-brain barrier after absorption, soothe vascular smooth muscle cells and increase blood supply to the brain.

The three materials mentioned above are known for their cognitive benefits, such as supporting memory, mental performance, and focus.

Our Alpha-GPC specifications

Alpha GPC 50 powder  25kg/Drum
Alpha GPC 50% granule  25kg/Drum
Alpha GPC liquid 85%  25kg/Drum
Alpha GPC powder 99%  1kg/Bag  25kg/Drum
Alpha-GPC softgel/Alpha-GPC capsule/Alpha-GPC tablet

Alpha-GPC Safety

Alpha-GPC is available in the United States as a dietary supplement. It has the status of ‘Generally Recognized as Safe’ (GRAS) as an ingredient in beverages and foods when consumed at a level not to exceed 196.2 mg/person/day.