5-Deazaflavin (2nd Generation)

5-Deazaflavin (2nd Generation)

Product Name 5-Deazaflavin (2nd Generation)
CAS Number 5997-14-7
Appearance Yellow to orange crystalline powder
Specifications ≥98% (HPLC)
Molecular Formula C11H7N3O2
Molecular Weight 213.19 g/mol
Solubility Soluble in DMSO, DMF; slightly soluble in methanol; practically insoluble in water
Storage Store at 2-8°C, protected from light and moisture

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Synonyms: 5-Deazaflavin, 5-Deazariboflavin, 7,8-Dimethyl-10-ribityl-5-deazaisoalloxazine, 5-Deazaflavin (2nd Generation), DAF, 5-Deaza-7,8-dimethyl-10-ribitylisoalloxazine

5-Deazaflavin (2nd Generation) is a synthetic analog of flavin coenzymes, featuring a carbon atom in place of nitrogen at the 5-position of the isoalloxazine ring. This modification imparts unique redox properties, making it a valuable tool in mechanistic studies of flavoenzymes and as a precursor for cofactor analogs. The “2nd Generation” designation refers to an optimized synthesis route that yields higher purity and improved batch-to-batch consistency, addressing the limitations of earlier preparations.

Our 5-Deazaflavin is produced under strict quality control, with each batch tested for identity, purity, and residual solvents. It is supplied as a fine crystalline powder, typically ≥98% pure by HPLC, and is available in gram to kilogram quantities to support both research and scale-up needs. The compound is widely used in academic and industrial R&D, particularly in enzymology, biophysical chemistry, and drug discovery where flavin mimics are required.

Product Highlights

  • High purity: ≥98% by HPLC, ensuring reliable performance in sensitive applications.
  • Optimized synthesis: 2nd generation process delivers consistent quality and reduced impurities.
  • Scalable supply: Available from grams to kilograms, with custom packaging options.
  • Regulatory support: Full documentation including COA, MSDS, and TDS for seamless compliance.
  • Technical expertise: Backed by our team’s deep experience in flavin chemistry and customer support.

Applications

  • Mechanistic studies of flavoenzymes and redox proteins.
  • Development of flavin-based biosensors and bioelectronic devices.
  • As a building block for modified cofactors in biocatalysis.
  • Reference standard for analytical method development.
  • Research on photoinduced electron transfer and radical chemistry.

Specifications

Parameter Specification
Assay (HPLC) ≥98.0%
Appearance Yellow to orange crystalline powder
Identification NMR, MS conform to structure
Loss on Drying ≤0.5%
Residue on Ignition ≤0.1%
Heavy Metals ≤10 ppm
Residual Solvents Meets ICH Q3C requirements

Ordering & Supply

  • Packaging: 1 g, 5 g, 10 g, 50 g, 100 g, 500 g, 1 kg in amber glass vials or bottles, sealed under argon.
  • MOQ: 1 g for standard packs; custom quantities available upon request.
  • Lead time: 3-5 business days (stock items)
  • Documentation: COA, MSDS, TDS, and additional analytical data available.

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