Ciprofloxacin

Synonimy: Cipro, Ciprobay, Ciproxin, Bay o 9867, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid

Ciprofloxacin is a synthetic broad-spectrum antibiotic belonging to the second-generation fluoroquinolone class. Since its introduction in the late 1980s, it has become a mainstay in both human and veterinary medicine, valued for its potent activity against a wide range of Gram-negative and Gram-positive bacteria. The compound works by inhibiting DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication and repair.

Chemically, ciprofloxacin is a fluorinated quinolone carboxylic acid. The presence of a fluorine atom at position 6 and a piperazine ring at position 7 enhances its potency and tissue penetration. It is often supplied as the hydrochloride salt or as the free base, depending on the intended formulation. The free base is practically insoluble in water, while the hydrochloride form offers improved aqueous solubility.

In the API market, ciprofloxacin is standardized to high purity levels, typically ≥98.0% as determined by HPLC. It is widely used in the production of oral tablets, intravenous solutions, ophthalmic drops, and veterinary products. Its broad-spectrum efficacy and favorable pharmacokinetic profile make it a key component in the fight against urinary tract infections, respiratory infections, and skin infections, among others.

Function & Mechanism

• DNA gyrase inhibition: Blocks bacterial DNA replication by targeting DNA gyrase, leading to cell death.
• Topoisomerase IV inhibition: Disrupts chromosomal partitioning during bacterial cell division.
• Broad-spectrum activity: Effective against both Gram-negative and Gram-positive pathogens, including Pseudomonas aeruginosa.
• Concentration-dependent killing: Exhibits rapid bactericidal action proportional to drug concentration.
• Post-antibiotic effect: Suppresses bacterial regrowth after exposure, allowing less frequent dosing.

Source & Standardization

• Źródło: Synthetic chemical synthesis
• Standardization: ≥98.0% (HPLC), meeting Ph. Eur., USP, and BP monographs
• Forms: Crystalline powder (free base or hydrochloride salt)
• Zastosowania: Oral solid dosage forms, sterile injectables, ophthalmic preparations, veterinary medicines

Quality Specifications (QC Tests)

Bulk Supply & Documentation

• Miesięczna wydajność: 20 MT
• Czas realizacji: 3–5 dni roboczych (towary dostępne w magazynie)
• Dokumentacja: COA, MSDS, TDS, DMF available upon request
• Opakowanie: 25 kg fiber drum with double polyethylene liner, or as per customer requirement

Najczęściej zadawane pytania

What is the minimum order quantity (MOQ) for Ciprofloxacin?

Our standard MOQ is 25 kg. For trial orders, we can accommodate smaller quantities; please contact our sales team for details.

How long does delivery take?

For stock items, delivery is typically 3-5 business days after order confirmation. We ship from our warehouse and provide tracking information promptly.

Do you provide a Certificate of Analysis (COA) and samples?

Yes, a COA is available for each batch. We also provide samples for quality evaluation upon request; sample delivery usually takes 1-2 days.

Contact & Ordering Information

• Company: LyvBio Co., Ltd.
• Address: Room 5-0203, Courtyard 205, Lianhu District, Xi’an, Shaanxi, China
• Email: info@lyvbio.com
• Phone: +86-29-65816888

send us your specification for a quotation.