Acetyl Tetrapeptide-5

Acetyl Tetrapeptide-5

Nazwa produktu Acetyl Tetrapeptide-5
Numer CAS 820959-17-9
Inne nazwy Acetyl Tetrapeptide-5, Acetyl Glutamyl-Methionyl-Glutaminyl-Arginine, Acetyl-EEMQRR
Wzór cząsteczkowy C20H34N8O9S
Masa cząsteczkowa 562.6 g/mol
Wygląd White to off-white lyophilized powder
Oznaczenie (HPLC) ≥98,01 TP3T
Rozpuszczalność Soluble in water, PBS, and aqueous buffers
Przechowywanie Store at -20°C, protect from light and moisture

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Acetyl Tetrapeptide-5 Structure

Synonyms: Acetyl Tetrapeptide-5, Acetyl Glutamyl-Methionyl-Glutaminyl-Arginine, Acetyl-EEMQRR, AHP-1, Acetyl Tetrapeptide-5 (Cosmetic Peptide)

Acetyl Tetrapeptide-5 is a synthetic tetrapeptide consisting of four amino acids—glutamic acid, methionine, glutamine, and arginine—with an acetyl group capping the N-terminus. This modification enhances stability and skin penetration, distinguishing it from unmodified peptides. Initially developed for cosmetic applications, it has gained traction in pharmaceutical research for its role in modulating cellular stress and inflammatory pathways.

Structurally, Acetyl Tetrapeptide-5 mimics a fragment of the human protein decorin, which regulates collagen fibrillogenesis and cell signaling. Its sequence, Ac-Glu-Met-Gln-Arg-NH2, is designed to interact with specific receptors involved in fibroblast activity and extracellular matrix remodeling. This peptide is often compared to other acetylated peptides like Acetyl Hexapeptide-8, but its unique sequence targets different biological processes, making it a versatile tool in both cosmetic and therapeutic formulations.

Our Acetyl Tetrapeptide-5 is manufactured via solid-phase peptide synthesis and purified using preparative HPLC to achieve a purity of ≥98%. It is available in research-grade and cGMP-compliant grades, suitable for a wide range of applications including anti-aging skincare, wound healing studies, and inflammation research. The product is supplied as a lyophilized powder to ensure long-term stability, with custom packaging options to meet diverse R&D and production needs.

Funkcja

  • Anti-inflammatory activity: Reduces pro-inflammatory cytokine production in skin cells.
  • Collagen synthesis promotion: Stimulates fibroblast proliferation and collagen I & III synthesis.
  • Ochrona antyoksydacyjna: Scavenges free radicals and protects against oxidative stress.
  • Skin barrier repair: Enhances keratinocyte differentiation and lipid barrier formation.
  • Wound healing support: Accelerates tissue regeneration in in vitro models.

Source & Standardization

  • Źródło: Synthetic peptide produced by solid-phase peptide synthesis (SPPS).
  • Extraction: Not applicable; chemically synthesized.
  • Standardization: ≥98.0% purity by HPLC; identity confirmed by mass spectrometry.
  • Forms: Lyophilized powder, sterile-filtered aqueous solution (custom).
  • Zastosowania: Cosmetic formulations (anti-aging, moisturizing), pharmaceutical research, cell culture studies.

Dane techniczne

Parametr Specyfikacja
Oznaczenie (HPLC) ≥98,01 TP3T
Identyfikacja Conforms to structure by MS
Strata przy suszeniu ≤5.0%
Popiół po spaleniu ≤1,01 TP3T
Metale ciężkie ≤10 ppm
Wartości graniczne dla mikroorganizmów Total aerobic count ≤100 CFU/g; Yeast & Mold ≤10 CFU/g
Endotoxin ≤5 EU/mg (for injectable grade)

Documentation & Supply

  • Miesięczna wydajność: 50 kg
  • Czas realizacji: 3–5 dni roboczych (towary dostępne w magazynie)
  • Dokumentacja: COA, MSDS, TDS, HPLC, MS, and stability data available upon request
  • Opakowanie: 1 g, 5 g, 10 g in amber glass vials; bulk quantities in polyethylene containers

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