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Synonyms: Calcium lactate, Calcium 2-hydroxypropanoate, Calcium DL-lactate, Lactic acid calcium salt, C6H10CaO6, CAS 814-80-2

Calcium lactate is the calcium salt of lactic acid, with the formula C6H10CaO6 and a molecular weight of 218.22 g/mol. The molecule consists of a central calcium ion coordinated to two lactate anions, each bearing a hydroxyl group adjacent to the carboxylate. This structure underpins its high water solubility and mild taste, properties that set it apart from less soluble calcium salts such as carbonate or phosphate. In aqueous solution, calcium lactate dissociates readily, releasing free calcium ions that are available for absorption without requiring gastric acidification.

Commercially, calcium lactate is produced by neutralizing lactic acid—typically derived from fermentation of carbohydrates—with a calcium source such as calcium carbonate or calcium hydroxide. The resulting solution is purified, concentrated, and crystallized to yield the pentahydrate or, upon drying, the anhydrous form. Both forms are offered in food, pharmaceutical, and technical grades. The pharmaceutical grade complies with monographs such as USP, EP, and BP, ensuring consistent assay, low heavy metals, and controlled particle size for direct compression and other solid dosage applications.

In the pharmaceutical and nutraceutical industries, calcium lactate serves as a bioavailable calcium supplement, an excipient in tablet formulations, and a buffering agent. Its compatibility with active ingredients and its ability to improve flowability in high-speed tableting make it a preferred choice for manufacturers. Additionally, calcium lactate finds use in food preservation, oral care products, and as a cross-linking agent in alginate systems. Research continues to explore its role in bone health, cardiology, and as a source of calcium in cell culture media.

Chemical Structure & Properties

Calcium lactate is a white, odorless crystalline powder that is freely soluble in water, giving a neutral to slightly alkaline solution. It exists as a pentahydrate (C6H10CaO6·5H2O) or in anhydrous form, with the pentahydrate being the more common commercial grade. The compound has a melting point of approximately 240°C (decomposition) for the anhydrous form. Its solubility profile allows for high loading in liquid formulations and rapid dissolution in physiological fluids. The lactate anion is metabolized in the liver to bicarbonate, providing a mild alkalizing effect without the gastrointestinal discomfort associated with calcium carbonate.

작용 기전

• Calcium supplementation: Dissociates into free Ca2+ ions, which are absorbed via active transport and passive diffusion in the small intestine, supporting bone mineralization and neuromuscular function.
• Buffering capacity: The lactate ion is metabolized to bicarbonate, contributing to acid-base balance and potentially reducing bone resorption.
• Excipient functionality: Acts as a binder and disintegrant in tablet formulations, improving compressibility and dissolution profiles.
• Preservation: In food systems, calcium lactate inhibits microbial growth by lowering water activity and interfering with cell membrane function.

Quality Specifications

Supply & Documentation

• Capacity: 500 metric tons per year
• 리드 타임: 3-5 business days (stock items)
• 문서: COA, MSDS, TDS, nutritional analysis, allergen statement, BSE/TSE-free declaration
• 포장: 25 kg net multi-wall paper bags with PE liner; 500 kg bulk bags; custom packaging available upon request

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